2020-07-03T11:08:04Z
2020-07-03T11:08:04Z
2017-08-04
2020-07-03T11:08:04Z
A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic 5-oxoester, bromination of the resulting oxazolopiperidone lactam, and a final stereoselective spirocyclization, is reported.
Article
Versió acceptada
Anglès
Síntesi orgànica; Enantiòmers; Oxidació; Compostos heterocíclics; Organic synthesis; Enantiomers; Oxidation; Heterocyclic compounds
American Chemical Society
Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.71301818
Organic Letters, 2017, vol. 19, num. 15, p. 4050-4053
https://doi.org/10.1021/acs.orglett.71301818
(c) American Chemical Society , 2017