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Política d’accés obert a la UB
Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.
Almodóvar Payá, Carmen; Guardiola Ripoll, Maria; Giralt López, Maria; Oscoz Irurozqui, Maitane; Canales Rodríguez, Erick Jorge; Madre, Mercè; Soler-Vidal, Joan; Ramiro, Núria; Callado, Luis F.; Arias Sampériz, Bárbara; Gallego González, Carmen; Pomarol-Clotet, Edith; Fatjó-Vilas Mestre, Mar (Publication date: 2026-03-25)
The expression of Neuritin-1 (NRN1), a neurotrophic factor crucial for neurodevelopment and synaptic plasticity, is enhanced by the Brain Derived Neurotrophic Factor (BDNF). Although the receptor of NRN1 remains unclear, ...
Gorría, Teresa; Sierra-Boada, Marina; Rojas, Mariam; Figueras, Carolina; Marín Martínez, Silvia; Madurga Díez, Sergio; Cascante i Serratosa, Marta; Maurel Santasusana, Joan (Publication date: 2026-03-03)
Although immune checkpoint inhibitor (ICI) therapy is currently the standard of care in microsatellite-unstable (MSI) metastatic colorectal cancer (CRC), ICI therapy, alone or in combination with other therapies, is not a ...
Rojas, Mariam; Gonzalez, Laura; Cascante i Serratosa, Marta; Maurel Santasusana, Joan (Publication date: 2026-02-02)
Metastatic colorectal cancer (mCRC) remains a highly lethal disease because resistance to chemotherapy and targeted agents—including anti-VEGF and anti-EGFR therapies—emerges rapidly and universally. In RAS‑mutant mCRC, ...
Rojas, Mariam; Manzi, Malena; Madurga Díez, Sergio; García Velásquez, Fernando Enrique; Romero, Maira Alejandra; Marín Martínez, Silvia; Cascante i Serratosa, Marta; Maurel Santasusana, Joan (Publication date: 2026-01-29)
Microsatellite-stable metastatic colorectal cancer (MSS mCRC) is currently treated with chemotherapy and targeted agents based on RAS and BRAF mutational status. Although these therapies offer initial benefit, most patients ...
Poyatos Dorado, Paula; Gratacòs-Aurich, Miquel; Aguilar, Daniel; Luque, Neus; Bonnin Vilaplana, Marc; Eizaguirre, Saioa; Cascante i Serratosa, Marta; Orriols Martínez, Ramon; Tura-Ceide, Olga (Publication date: 2026-01-27)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused significant global morbidity since 2019. Long COVID, characterized by persistent symptoms after acute infection, may involve endothelial injury. We ...
Pulido, Daniel; Casadó Anguera, Verònica; Pérez-Benito, Laura; Moreno Guillén, Estefanía; Cordomí, Arnau; López, Laura; Cortés Tejedor, Antonio; Ferré, Sergi; Pardo, Leonardo; Casadó, Vicent; Royo Expósito, Miriam (Publication date: 2026-01-23)
Bivalent ligands have emerged as chemical tools to study G protein-coupled receptor dimers. Using a combination of computational, chemical, and biochemical tools, here we describe the design of bivalent ligand 13 with high ...
Idrees, Rabia; Subirats i Vila, Xavier; Amézqueta, Susana; Rosés Pascual, Martí (Publication date: 2026-01-16)
This study presents a fast method for the characterization of solute-solvent interactions in micellar and microemulsion electrokinetic chromatography based on the linear solvation energy relationships proposed by Abraham. ...
San Martín-Gonzalez, Nerea; Moya-Higueras, Jorge; Eixarch Roca, Elisenda; Castro-Quintas, Águeda; Marques-Feixa, Laia; Crispi Brillas, Fàtima; Daura-Corral, Maria; de la Fuente-Tomás, Lorena; Monteserín-García, José Luis; García Portilla, María Paz; Fañanás Saura, Lourdes (Publication date: 2024-12-03)
Background: Maternal childhood maltreatment (CM) has been repeatedly associated with negative offspring's emotional outcomes. The dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis has emerged as the main ...
Benzoni, Patrizia; Campostrini, Giulia; Landi, Sara; Bertini, Valeria; Marchina, Eleonora; Iascone, Maria; Ahlberg, Gustav; Olesen, Morten Salling; Crescini, Elisabetta; Mora, Cristina; Bisleri, Gianluigi; Muneretto, Claudio; Ronca, Roberto; Presta, Marco; Poliani, Pier Luigi; Piovani, Giovanna; Verardi, Rosanna; Pasquale, Elisa Di; Consiglio, Antonella; Raya Chamorro, Ángel; Torre, Eleonora; Lodrini, Alessandra Maria; Milanesi, Raffaella; Rocchetti, Marcella; Baruscotti, Mirko; DiFrancesco, Dario; Memo, Maurizio; Barbuti, Andrea; Dell'Era, Patrizia (Publication date: 2021-05-03)
Aims: Atrial fibrillation (AF) is the most common type of cardiac arrhythmias, whose incidence is likely to increase with the aging of the population. It is considered a progressive condition, frequently observed as a ...
Bayó Puxan, Neus; Terrasso, Ana Paula; Creyssels, Sophie; Simão, Daniel; Begon Pescia, Christina; Lavigne, Marina; Salinas, Sara; Bernex, Florence; Bosch, Assumpció; Kalatzis, Vasiliki; Levade, Thierry; Cuervo, Ana Maria; Lory, Philippe; Consiglio, Antonella; Brito, Catarina (Publication date: 2020-11-13)
Mucopolysaccharidosis type VII (MPS VII) is a lysosomal storage disease caused by deficient β-glucuronidase (β-gluc) activity. Significantly reduced β-gluc activity leads to accumulation of glycosaminoglycans (GAGs) in ...
Peralta, Víctor; Moreno-Izco, Lucía; García de Jalón, Elena; Sánchez Torres, Ana M.; Peralta, David; Janda, Lucía; Cuesta, Manuel J.; SEGPEPs group; Ansorena, Xabier; Ballesteros, Alejandro; Chato, Julen; Fañanás Saura, Lourdes; Gil-Berrozpe, Gustavo; Giné-Servé, Eloi; Lorente, Ruth; Papiol, Sergi; Ribeiro, María; Rosado, Esther; Rosero, Ángela (Publication date: 2025-07-28)
Background: Suicidal thoughts and behaviors (STBs) are a major concern in people with psychotic disorders. There is a need to examine their prevalence over long-term follow-up after first-episode psychosis (FEP) and determine ...
Menendez, Sergio; Camus, Suzanne; Herreria, Aida; Paramonov, Ida; Morera, Laura B.; Collado, Manuel; Pekarik, Vlad; Maceda, Iago; Edel, Michael John; Consiglio, Antonella; Sánchez-Danés, Adriana; Li, Han; Serrano Marugán, Manuel; Izpisúa Belmonte, Juan Carlos (Publication date: 2017-02-16)
Embryonic stem (ES) cells and induced pluripotent stem (iPS) cells represent a promising therapeutic tool for many diseases, including aged tissues and organs at high risk of failure. However, the intrinsic self-renewal ...
Manzanares, Alejandro; Restrepo-Perdomo, Camilo A.; Botteri, Gaia; Castillo Ecija, Helena; Pascual Pasto, Guillem; Cano, Francesc; García Álvarez, Laura; Monterrubio Martínez, Carles; Ruiz, Bonaventura; Vázquez Carrera, Manuel; Suñol, Mariona; Mora Graupera, Jaume; Tornero, Jose A.; Sosnik, Alejandro; Carcaboso, Ángel M. (Publication date: 2019-11-05)
Delivery of chemotherapy in the surgical bed has shown preclinical activity to control cancer progression upon subtotal resection of pediatric solid tumors, but whether this new treatment is safe for tumor‐adjacent healthy ...
Irimia Martínez, Manuel; Piñeiro, Cristina; Maeso, Ignacio; Gómez Skarmeta, Jose Luis; Casares, Fernando; Garcia Fernández, Jordi (Publication date: 2010-09-21)
Background: The zona limitans intrathalamica (ZLI) and the isthmus organizer (IsO) are two major secondary organizers of vertebrate brain development. These organizers are located at the interface of the expression domains ...
Martínez-Gil, Núria; Roca Ayats, Neus; Atalay, Nurgül; Pineda Moncusí, Marta; Garcia Giralt, Natàlia; Van Hul, Wim; Boudin, Eveline; Ovejero, Diana; Mellibovsky, Leonardo; Nogués Solán, Xavier; Díez Pérez, Adolfo; Grinberg Vaisman, Daniel Raúl; Balcells Comas, Susan (Publication date: 2021-06-01)
The DKK1 gene encodes an extracellular inhibitor of the Wnt pathway with an important role in bone tissue development, bone homeostasis, and different critical aspects of bone biology. Several BMD genome-wide association ...
Abad, Sonia; Junyent Herena, Fèlix; Auladell i Costa, M. Carme; Pubill Sánchez, David; Pallàs i Llibería, Mercè, 1964-; Camarasa García, Jordi; Escubedo Rafa, Elena; Camins Espuny, Antoni (Publication date: 2015-05-13)
Abstract Kainic acid (KA) causes seizures and neuronal loss in the hippocampus. The present study investigated whether a recreational schedule of 3,4-methylenedioxymethamphetamine (MDMA) favours the development of a seizure ...
Sandoval, Viviana; Femenias, Antoni; Martínez Garza, Úrsula; Sanz Lamora, Héctor; Castagnini, Juan Manuel; Quifer Rada, Paola; Lamuela Raventós, Rosa Ma.; Marrero González, Pedro F.; Haro Bautista, Diego; Relat Pardo, Joana (Publication date: 2020-05-07)
Maqui (Aristotelia Chilensis) berry features a unique profile of anthocyanidins that includes high amounts of delphinidin-3-O-sambubioside-5-O-glucoside and delphinidin-3-O-sambubioside and has shown positive effects on ...
Benitez Amaro, Aleyda; Revuelta López, Elena; Bornachea, Olga; Cedó Giné, Lídia; Vea, Àngela; Herrero Rodríguez, Laura; Roglans i Ribas, Núria; Soler Botija, Carolina; Gonzalo Calvo, David de; Nasarre, Laura; Camino López, Sandra; García, Eduardo; Mato, Eugenia; Blanco Vaca, Francisco; Bayés Genís, Antoni; Sebastián Muñoz, David; Laguna Egea, Juan Carlos; Serra i Cucurull, Dolors; Zorzano Olarte, Antonio; Escolà Gil, Joan Carles; Llorente Cortés, Vicenta (Publication date: 2020-05-22)
Background: Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty acid metabolism and glucose homeostasis. In the context of dyslipemia, LRP1 is upregulated in the heart. Our aim was to evaluate ...
Yuan, Luping; Springer, Jochen; Palus, Sandra; Busquets Rius, Sílvia; Jové, Queralt; Alves de Lima Junior, Edson; Anker, Markus S.; von Haehling, Stephan; Álvarez Ladrón, Natalia; Millman, Oliver; Oosterlee, Annemijn; Szymczyk, Agata; López-Soriano, Francisco J.; Anker, Stefan D.; Coats, Andrew J. S.; Argilés Huguet, Josep Ma. (Publication date: 2025-02-24)
Background: Beta-blockers and selected stereoisomers of beta-blockers, like bisoprolol and S-pindolol (ACM-001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of ...
Sangüesa Puigventós, Gemma; Baena Muñoz, Miguel; Hutter, Natalia; Montañés, José Carlos; Sánchez, Rosa María; Roglans i Ribas, Núria; Laguna Egea, Juan Carlos; Alegret i Jordà, Marta (Publication date: 2018-03-16)
A high consumption of fat and simple sugars, especially fructose, has been related to the development of insulin resistance, but the mechanisms involved in the effects of these nutrients are not fully understood. This study ...