Synthesis and Antiviral Evaluation of Bisnoradamantane Sulfites and Related Compounds

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2020-06-04T16:33:33Z

2020-06-04T16:33:33Z

2011-10-02

2020-06-04T16:33:33Z

Resumen

The reaction of a series of 1,2-diols with thionyl chloride led to bisnoradamantane sulfites in very good yields. The reaction has also been applied to related polycyclic scaffolds. The compounds have been tested for antiviral activity but none of them showed to be active. Several attempts to generate and trap SO from these polycyclic sulfites have been unsuccessful.

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Bentham Science Publishers

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Versió postprint del document publicat a: https://doi.org/10.2174/157340611794859299

Medicinal Chemistry, 2011, vol. 7, num. 2, p. 135-140

https://doi.org/10.2174/157340611794859299

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(c) Bentham Science Publishers, 2011