PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders

dc.contributor.author
Palomer Tarridas, Francesc Xavier
dc.contributor.author
Barroso Fernández, Emma
dc.contributor.author
Pizarro Delgado, Javier
dc.contributor.author
Peña, Lucía
dc.contributor.author
Botteri, Gaia
dc.contributor.author
Zarei, Mohammad
dc.contributor.author
Aguilar, David
dc.contributor.author
Montori Grau, Marta
dc.contributor.author
Vázquez Carrera, Manuel
dc.date.issued
2020-04-27T15:00:52Z
dc.date.issued
2020-04-27T15:00:52Z
dc.date.issued
2018-03-20
dc.date.issued
2020-04-27T15:00:52Z
dc.identifier
1661-6596
dc.identifier
https://hdl.handle.net/2445/157699
dc.identifier
680789
dc.identifier
29558390
dc.description.abstract
Research in recent years on peroxisome proliferator-activated receptor (PPAR)β/δ indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARβ/δ activation might help prevent the development of metabolic disorders, including obesity, dyslipidaemia, type 2 diabetes mellitus and non-alcoholic fatty liver disease. This review highlights research findings on the PPARβ/δ regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. It also describes the potential of the pharmacological activation of PPARβ/δ as a treatment for human metabolic disorders
dc.format
14 p.
dc.format
application/pdf
dc.language
eng
dc.publisher
MDPI
dc.relation
Reproducció del document publicat a: https://doi.org/10.3390/ijms19030913
dc.relation
International Journal of Molecular Sciences, 2018, vol. 19, num. 3, p. 913
dc.relation
https://doi.org/10.3390/ijms19030913
dc.rights
cc-by (c) Palomer Tarridas, Francesc Xavier et al., 2018
dc.rights
http://creativecommons.org/licenses/by/3.0/es
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Homeòstasi
dc.subject
Obesitat
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Diabetis
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Metabolisme cel·lular
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Farmacologia
dc.subject
Homeostasis
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Obesity
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Diabetes
dc.subject
Cell metabolism
dc.subject
Pharmacology
dc.title
PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion


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