2020-04-27T15:00:52Z
2020-04-27T15:00:52Z
2018-03-20
2020-04-27T15:00:52Z
Research in recent years on peroxisome proliferator-activated receptor (PPAR)β/δ indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARβ/δ activation might help prevent the development of metabolic disorders, including obesity, dyslipidaemia, type 2 diabetes mellitus and non-alcoholic fatty liver disease. This review highlights research findings on the PPARβ/δ regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. It also describes the potential of the pharmacological activation of PPARβ/δ as a treatment for human metabolic disorders
Article
Published version
English
Homeòstasi; Obesitat; Diabetis; Metabolisme cel·lular; Farmacologia; Homeostasis; Obesity; Diabetes; Cell metabolism; Pharmacology
MDPI
Reproducció del document publicat a: https://doi.org/10.3390/ijms19030913
International Journal of Molecular Sciences, 2018, vol. 19, num. 3, p. 913
https://doi.org/10.3390/ijms19030913
cc-by (c) Palomer Tarridas, Francesc Xavier et al., 2018
http://creativecommons.org/licenses/by/3.0/es