Universitat de Barcelona
2019-01-29T12:04:46Z
2019-01-29T12:04:46Z
2015-02-10
2019-01-29T12:04:46Z
A new strategy for the synthesis of tetrahydroisoquinolines based on the Pd(0)-catalyzed intramolecular α-arylation of sulfones is reported. The combination of this Pd-catalyzed reaction with intermolecular Michael and aza-Michael reactions allows the development of two- and three-step domino processes to synthesize diversely functionalized scaffolds from readily available starting materials. KEYWORDS: arylation; domino reactions; nitrogen heterocycles; palladium; sulfones
Article
Versió acceptada
Anglès
Compostos heterocíclics; Compostos de nitrogen; Compostos de sofre; Pal·ladi (Element químic); Síntesi orgànica; Heterocyclic compounds; Nitrogen compounds; Sulfur compounds; Palladium; Organic synthesis
Wiley-VCH
Versió postprint del document publicat a: https://doi.org/10.1002/chem.201406305
Chemistry-A European Journal, 2015, vol. 21, num. 12, p. 4580-4584
https://doi.org/10.1002/chem.201406305
(c) Wiley-VCH, 2015
