dc.contributor.author
Solé Arjó, Daniel
dc.contributor.author
Pérez Janer, Ferran
dc.contributor.author
Mancuso, Raffaella
dc.date.issued
2019-01-29T12:04:46Z
dc.date.issued
2019-01-29T12:04:46Z
dc.date.issued
2015-02-10
dc.date.issued
2019-01-29T12:04:46Z
dc.identifier
https://hdl.handle.net/2445/127700
dc.description.abstract
A new strategy for the synthesis of tetrahydroisoquinolines based on the Pd(0)-catalyzed intramolecular α-arylation of sulfones is reported. The combination of this Pd-catalyzed reaction with intermolecular Michael and aza-Michael reactions allows the development of two- and three-step domino processes to synthesize diversely functionalized scaffolds from readily available starting materials. KEYWORDS: arylation; domino reactions; nitrogen heterocycles; palladium; sulfones
dc.format
application/pdf
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1002/chem.201406305
dc.relation
Chemistry-A European Journal, 2015, vol. 21, num. 12, p. 4580-4584
dc.relation
https://doi.org/10.1002/chem.201406305
dc.rights
(c) Wiley-VCH, 2015
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Compostos heterocíclics
dc.subject
Compostos de nitrogen
dc.subject
Compostos de sofre
dc.subject
Pal·ladi (Element químic)
dc.subject
Síntesi orgànica
dc.subject
Heterocyclic compounds
dc.subject
Nitrogen compounds
dc.subject
Sulfur compounds
dc.subject
Organic synthesis
dc.title
Pd0-Catalyzed Intramoleculara-Arylation of Sulfones: Domino Reactions in the Synthesis of Functionalized Tetrahydroisoquinolines
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
