Patologia i Terapèutica Experimental: Recent submissions
Now showing items 161-180 of 1057
Moderate and severe dental fluorosis in the rural population of Anantapur, India: change in their biological susceptibility?
Dental fluorosis affects the quality of life. A cross-sectional, observational study was conducted in a community affected by endemic fluorosis for several generations with a conserved biological and social environment. ...
Biochemical, ultrastructural, and reversiblity studies on Huntingtin filaments isolated from mouse and human brain
Huntington's disease (HD) and eight additional inherited neurological disorders are caused by CAG triplet-repeat expansions leading to expanded polyglutamine-sequences in their respective proteins. These triplet-CAG repeat ...
Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa
Background: protein Ser/Thr Phosphatase PPP1CC2 is an alternatively spliced isoform of PPP1C that is highly enriched in testis and selectively expressed in sperm. Addition of the phosphatase inhibitor toxins okadaic acid ...
Chronic hypoxia induced ultrastructural changes in the rat adrenal zona glomerulosa
The adrenal cortex plays an important role in adaptation to various forms of stress, including hypoxia. While physiological changes in the aldosterone metabolism during hypoxia have been extensively described, few studies ...
Endometrial epithelial cell organoids as tools for studying the CD39 family of enzymes and for validating enzyme inhibitors
Extracellular adenosine triphosphate (ATP) conducts a complex dynamic system of broadly represented cell signaling. Ectonucleotidases are the enzymes with nucleotide hydrolytic ability that regulate ATP levels in physiological ...
Mouthrinses: a comparative microbiological study
This study was performed in order to evaluate the efficacy of different mouthrinses whose use is extended in Spain. Six different antiseptic mouthrinses were studied by means of determination of Minimal Inhibitory Concentration ...
El examen MIR y su contenido en anatomía humana, bioestadística y epidemiología: evolución y accesibilidad para el opositor/a
Fundamentos: El examen MIR constituye actualmente el único medio de selección de candidatos para la formación de médicos especialistas en España. Consta de 260 preguntas (10 de ellas son de reserva) de las distintas ...
Full-mouth periodontal examination prior to and after nonsurgical treatment in chronic periodontitis patients.
Chronic periodontitis is a pathological condition characterized by loss of the supporting tissues of the teeth. The aim of this study was to evaluate the distribution of disease sites in different areas of mouth, prior to ...
Impacto de la legalización del consumo recreativo del cannabis
En los últimos años se han producido importantes cambios legislativos en numerosos países respecto al consumo de cannabis con fines medicinales y/o recreativos, que han facilitado su accesibilidad. Actualmente, Uruguay, ...
Anatomía de los ligamentos del tobillo (Comunicación oficial 1 (SECOT, Madrid, octubre 2004))
La anatomía y biomecánica de los ligamentos de tobillo sigue siendo motivo de interés pues es requisito indispensable para el diagnóstico y adecuado tratamiento de sus lesiones, ya que éstas son una de las mayores causas ...
Multilingual Naming
Bi/multilingualism refers to the ability to use two or more languages in everyday life. Increasing interest has been paid to unveil the neural basis of bilingual language processing; however, the brain representation of ...
Cachexia-associated adipose tissue morphological rearrangement in gastrointestinal cancer patients
Background and aims: Cachexia is a syndrome characterized by marked involuntary loss of body weight. Recently, adipose tissue (AT) wasting has been shown to occur before the appearance of other classical cachexia markers. ...
Enrichment cultures should be performed in the detection of bacterial oral human pathogens in DUWLs
Water delivered by dental units during routine dental practice is densely contaminated by bacteria. The aim of this study was to determine actual isolation of the microorganisms sprayed from Dental Unit Water Lines (DUWLs) ...
"In vitro" comparative experimental study of antimicrobial action of mouth washing products
Regular use of mouth rinses modifies the oral habitat, since bacterial populations are submitted to a high selective pressure during the treatment exercised by the active presence of the disinfectant. Mostly mouth rinses ...
Small molecule anionophores promote transmembrane anion permeation matching CFTR activity
Anion selective ionophores, anionophores, are small molecules capable of facilitating the transmembrane transport of anions. Inspired in the structure of natural product prodigiosin, four novel anionophores 1a-d, including ...
Dificultad en la comunicación del riesgo de padecer cáncer hereditario.
Diferentes estudios han demostrado que, en ocasiones, los pacientes tienen dificultades a la hora de entender lo que el médico quiere comunicarles. El presente artículo intenta reflexionar sobre cuáles son los determinantes ...
Cirugía plástica de las malformaciones congénitas del aparato genital: anomalías de diferenciación sexual
Se presenta la necesidad de tratar estas malformaciones congénitas en una unidad hospitalaria en la que el pediatra realiza la labor coordinadora, diagnóstica y de tratamiento médico y el cirujano plástico las plastias ...
Valoración de la aplicación del eLearning en la docencia de Farmacologia
La implementació del eLearning es eficient i està justificada si prèviament s'evoluciona de docència expositiva a docència funcional. Aquesta proporciona informació als docents orientant sobre el seu impacte i eficàcia i ...
Inervación sensitiva y crecimiento mandibular: propuesta de modelo experimental para acceso quirúrgico al nervio alveolar inferior preservando estructuras musculoesqueléticas en Conejo New Zealand White pos-destetados
Numerosos estudios reflejan vínculos entre la inervación sensitiva y el desarrollo de la estructura ósea mandibular. Con la finalidad de obtener un modelo in vivo para estudiar el efecto de la alteración de la inervación ...
Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology
Synaptic dysfunction is an early feature in Alzheimer's disease (AD) pathogenesis and a major morphological correlate of memory deficits. Given the main synaptic location of N-methyl-D-aspartate receptors (NMDARs), their ...
