Universitat de Barcelona
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Política d’accés obert a la UB
Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.
Vaccinia virus (VACV) is widely used as a vaccine and oncolytic vector due to its safety profile and its capacity to accommodate exogenous DNA. However, its compact genome offers limited for transgene insertion without ...
This study aimed to describe the shoulder anatomy, together with the anatomical relationships in adults and early stages of development. The shoulder muscles were studied from ultrasound, anatomical, and microscopic ...
Background: Colorectal cancer (CRC) remains a major global health concern, partly due to resistance to therapy and the lack of new effective treatments for advanced disease. The combination of 5-Fluorouracil (5FU, a ...
Rationale: Tracheobronchial stents are used to treat central airway obstruction but frequently develop bacterial colonization that can lead to infection.Objectives: To identify the microorganisms responsible for stent ...
Antimicrobial resistance is widely recognized as one of the major challenges of public health worldwide, as infections by multidrug-resistant (MDR) bacteria have reached worrisome levels. Three levels of antibiotic resistance ...
Background: New fluid biomarkers for Alzheimer's disease (AD) that reveal synaptic and neural network dysfunctions are needed for clinical practice and therapeutic trial design. Dense core vesicle (DCV) cargos are promising ...
Dravet syndrome (DS) is a developmental epileptic encephalopathy (DEE) driven by pathogenic variants in the SCN1A gene. Brain organoids (BOs) have emerged as reliable models for neurodevelopmental genetic disorders, ...
Therapy resistance in human cancers is a major limitation in Clinical Oncology. In this regard, overexpression of anti-apoptotic proteins, such as survivin, has been described in several tumors, contributing to this clinical ...
Purpose: To interrogate animal physiology in vivo, there is a lack of non-genetic methods to control the activity of endogenous proteins with pharmacological and spatiotemporal precision. To address this need, we recently ...
GATA2 deficiency is a monogenic transcriptopathy disorder characterized by bone marrow failure (BMF), immunodeficiency, and a high risk of developing myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML). Although ...
In this review, we evaluate the knowledge gained so far about the neural bases of multilingual language processing obtained mainly through imaging and electrical stimulation mapping (ESM). We attempt to answer some key ...
Background: Resting-state functional connectivity magnetic resonance imaging (rs-fMRI) is a sensitive tool for detecting early brain changes associated with Alzheimer's disease, even in its preclinical stages. Amnestic ...
Heavy and daily use of cannabis with high contents of Delta 9-tetrahydrocannabinol (THC) during adolescence is associated with an increased risk of developing psychotic disorders later in life. Here, we treated mice with ...
We read with great interest the recent report in the American Journal of Cardiology by Hoetzer et al.1 The investigators addressed the question of whether in healthy, middle-aged subjects circulating endothelial progenitor ...
Suprascapular neuropathy is an important factor contributing to shoulder pain. Given the prevalence of nerve injury and nerve block in the suprascapular notch region, as well as the frequency of arthroscopic procedures on ...
Compartir ideas. La universidad va al instituto es un proyecto de aprendizaje servicio transversal de la Universidad de Barcelona. Este representa una propuesta de aprendizaje servicio que bajo una estructura común permite ...
Se efectúa la presentación del proyecto AEDMI, acrónimo de Aproximación Epidemiológica al Diagnóstico Médico Informatizado. EL proyecto tiene como objetivo el desarrollo de un sistema experto de ayuda al diagnóstico basado ...
Se presenta el estudio del desarrollo embriológico facial utilizando 10 embriones humanos cuyas edades oscilaban entre los 24 dlas (3 mm) y los 50 días (50 mm). Se valoró la evolución de los procesos naso-medial y naso-lateral ...
The main difficulty in the successful treatment of metastatic melanoma is that this type of cancer is known to be resistant to chemotherapy. Chemotherapy remains the treatment of choice, and dacarbazine (DTIC) is the best ...
Mutations in PARK7/DJ-1 gene are associated to autosomal recessive early onset forms of Parkinson"s disease (PD). Although large gene deletions have been linked to a loss-of-function phenotype, the pathogenic mechanism of ...
