Patologia i Terapèutica Experimental: Recent submissions
Now showing items 201-220 of 1057
Disease isolates of Streptococcus pseudopneumoniae and non-typeable S. pneumoniae presumptively identified as atypical S. pneumoniae in Spain
We aimed to obtain insights on the nature of a collection of isolates presumptively identified as atypical Streptococcus pneumoniae recovered from invasive and non-invasive infections in Spain. One-hundred and thirty-two ...
Short report. The AIDIT and IMPACT conference 2006: Outcomes and future directions
IMPACT (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in BRCA1/2 mutation carriers and controls) is an international collaboration investigating the utility of targeted ...
Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal glial networks
Extrasynaptic neurotransmission is an important short distance form of volume transmission (VT) and describes the extracellular diffusion of transmitters and modulators after synaptic spillover or extrasynaptic release in ...
Effects of the proapoptotic drug prodigiosin on cell cycle-related proteins in Jurkat T cells
Prodigiosin (PG) is a red pigment produced by Serratia marcescens with immunosuppressive and apoptotic activities. In this study, we sought to examine the effect of PG on cell cycle-related proteins. The antiproliferative ...
Actividad antibacteriana de la Bencidamina HCl
En el presente trabajo se valora la eficacia antibacteriana del colutorio Tantum verde® y la de su, presuntamente, único principio activo, la bencidamina clorhidrato. Para ello, se ensayó la actividad in vitro de la ...
Assessing self-reported adherence to HIV therapy by questionnaire: the SERAD (Self-Reported Adherence) study
The relationship between adherence to highly active antiretroviral therapy (HAART) and RNA-HIV viral load outcomes has been extensively shown. Although there are different procedures for assessing treatment adherence, there ...
Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse
The reelin gene encodes an extracellular protein that is crucial for neuronal migration in laminated brain regions. To gain insights into the functions of Reelin, we performed high-resolution in situ hybridization analyses ...
Evaluation of periodontal health in healthy primary molars in comparison with molars restored with stainless steel crowns
Background: Children with large carious lesions are best treated with stainless-steel crowns (SSC). However, few studies have evaluated periodontal health after SSC restorations. Methods: A total of 33 children between the ...
Microvascularización de los tumores cerebrales y factor angiogénico en el líquido cefalorraquídeo tumoral
Utilizando el método de tinción de la bencidina se realizó un estudio sobre las características morfológicas de la microvascularización de los tumores cerebrales; paralelamente, en la membrana corioalantoidea de embriones ...
Exocytosis at the ribbon synapse of retinal bipolar cells studied in patches of presynaptic membrane
The distribution of exocytic sites and ion channels in the synaptic terminal of retinal bipolar cells was investigated by measuring capacitance and conductance changes in cell-attached patches of presynaptic membrane. Patch ...
Bacterial membrane injuries induced by lactacin F and nisin
The combined action of nisin and lactacin F, two bacteriocins produced by lactic acid bacteria, is additive. In this report, the basis of this effect is examined. Channels formed by lactacin F were studied by experiments ...
Chromosome X-wide analysis of positive selection in human populations: common and private signals of selection and its impact on inactivated genes and enhancers
The ability of detecting adaptive (positive) selection in the genome has opened the possibility of understanding the genetic basis of population-specific adaptations genome-wide. Here, we present the analysis of recent ...
Docencia sobre las fuentes comerciales de información de medicamentos y opinión de los estudiantes de medicina
Objetivo: Conocer la opinión de los estudiantes sobre un seminario que enseña la interacción de los médicos con las fuentes comerciales de información de los medicamentos. Sujetos y métodos: Se realizó una encuesta a los ...
The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine
Microseminoprotein-beta (MSMB) regulates apoptosis and using genome-wide association studies the rs10993994 single nucleotide polymorphism in the MSMB promoter has been linked to an increased risk of developing prostate ...
A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer
Background: prevention of unnecessary biopsies and overtreatment of indolent disease remains a challenge in the management of prostate cancer. Novel non-invasive tests that can identify clinically significant (intermediate-risk ...
Block of transmitter release by botulinum C1 actiuon on syntaxin at the squid giant synapse
Electrophysiological, morphological, and biochemical approaches were combined to study the effect of the presynaptic injection of the light chain of botulinum toxin C1 into the squid giant synapse. Presynaptic injection ...
A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle
Myogenin is the dominant transcriptional regulator of embryonic and fetal muscle differentiation and during maturation is profoundly down-regulated. We show that a highly conserved 17-bp DNA cis-acting sequence element ...
Cytotoxicity comparison of Bio C Sealer against multiple root canal sealers
Background: The aim of this study was to compare the cytotoxicity of calcium silicate-based endodontic sealer, Bio-C® Sealer, with other calcium silicate-based sealers: BioRoot¿ RCS, one silicon-based sealer combined with ...
Neuroprotection with Hypothermia and Allopurinol in an animal model of hypoxic-ischemic injury: Is it a gender question?
Abstract Background Hypoxic-ischemic encephalopathy (HIE) is one of the most important causes of neonatal brain injury. Therapeutic hypothermia (TH) is the standard treatment for term newborns after perinatal hypoxic ...
Fluoromodule-based reporter/probes designed for in vivo fluorescence imaging
Optical imaging of whole, living animals has proven to be a powerful tool in multiple areas of preclinical research and has allowed noninvasive monitoring of immune responses, tumor and pathogen growth, and treatment ...
