Farmàcia, Tecnologia Farmacèutica i Fisicoquímica: Enviaments recents
Ara mostrant els elements 41-60 de 664
Entrapment of Citrus limon var. pompia Essential Oil or Pure Citral in Liposomes Tailored as Mouthwash for the Treatment of Oral Cavity Diseases
This work aimed at developing a mouthwash based on liposomes loading Citrus limon var. pompia essential oil or citral to treat oropharyngeal diseases. Vesicles were prepared by dispersing phosphatidylcholine and pompia ...
Mangifera indica L. extract tablets supplementation in patients with knee osteoarthritis pain. A controlled pilot study.
Context: Several experimental results and clinical reports using Mangifera indica L extract (MSBE) suggest its potential utility in osteoarthritis (OA) mixed pain. Aims: To examine the possible therapeutic effects and ...
Developing Transdermal Applications of Ketorolac Tromethamine Entrapped in Stimuli Sensitive Block Copolymer Hydrogels
Purpose: In order to obtain dermal vehicles of ketorolac tromethamine (KT) for the local treatment of inflammation and restrict undesirable side effects of systemic levels hydrogels (HGs) of poloxamer and carbomer were ...
SeDeM as a Tool to Validate Drug Substance Manufacturing Processes and Assess Scalability and Suitability for Direct Compression: Supplier Screening
During the development of an oral solid form of a drug substance, a thorough understanding of the critical material attributes is necessary, as the physical properties of the active pharmaceutical ingredient (API) can ...
Release of Ropinirole in Acrylate Transdermal Patches: Mutual Interactions Between Formulation Variables
The aim of this study is to evaluate the cooperative interactions between formulation variables of ropinirole transdermal patches and characterize the effects of drug loading and crystallinity, degree of ionization and ...
Endogenous Antioxidant Cocktail Loaded Hydrogel for Topical Wound Healing of Burns
Abstract: The main goal of this work is the study of the skin wound healing efficacy of an antioxidant cocktail consisting of vitamins A, D, E and the endogenous pineal hormone melatonin (MLT), with all of these loaded ...
Comparative Study of Donepezil-Loaded Formulations for the Treatment of Alzheimer's Disease by Nasal Administration
Abstract: Alzheimer's disease is characterized by a progressive deterioration of neurons resulting in a steady loss of cognitive functions and memory. Many treatments encounter the challenge of overcoming the blood-brain ...
Molecular simulations of globins: Exploring the relationship between structure, dynamics and function
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32392
Characterization of Ligand Binding in Human Serum Albumin from Atomistic Energy Transfer Simulations
Förster resonance energy transfer (FRET) is a key biophysical method for probing nanometer‑scale distances in biomolecular systems, but its direct application to protein–ligand complexes suffers from substantial biases due ...
Development of a mucoadhesive delivery system for control release of doxepin with application in vaginal pain relief assciated with gynecological surgery.
The main purpose of this study was to develop a semisolid mucoadhesive formulation for the non-invasive vaginal administration of doxepin (DOX) for relief of pain derived from the scarring process after surgery. An orafix® ...
Euphorbia paniculata subsp. calcicola U.Schwarzer & Vicens subsp. nova (Euphorbiaceae), a new taxon of the southwestern Portugal
[eng] A new subspecies of E. paniculata Desf., E. paniculata subsp. calcicola U.Schwarzer & Vicens subsp. nov., is described. It grows in the proximity of the town of Sagres southwestern Portugal on calcareous substrate. ...
Pharmacy student's engagement, performance and perceptions in a pilot study of cooperative learning applied to 'introduction to the galenic pharmacy' subject
Introduction to the Galenic Pharmacy (IFG) is a required subject of first-year (2nd semester) of Pharmacy Degree of the University of Barcelona (UB). This subject is very conceptual and descrip tive and contains many ...
Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent ...
Anàlisis de la dispensació d'ustekinumab des del Servei de Farmàcia per a pacients externs amb psoriasi o artritis psoriàsica
Objectiu: Els biològics han revolucionat l a teràpia de l'espectre de les malalties psoriàsiques. L'objectiu d'aquest estudi és analitzar l'administració d'ustekinumab a pacients ambulatoris amb psoriasi o artritis psoriàsica. ...
Unraveling the role of thermal fluctuations on the exciton structure of the cryptophyte PC612 and PC645 photosynthetic antenna complexes
Protein scaffolds play a crucial role in tuning the light harvesting properties of photosynthetic pigment-protein complexes, influencing pigment-protein and pigment-pigment excitonic interactions. Here, we investigate the ...
Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors
Background: The amyloid-β peptide (Aβ42) is the main component of the inter-neuronal amyloid plaques characteristic of Alzheimer's disease (AD). The mechanism by which Aβ42 and other amyloid peptides assemble into insoluble ...
Spatial and Electronic Correlations in the PE545 Light-Harvesting Complex
The recent discovery of long-lasting quantum coherence effects in photosynthetic pigment-protein complexes has challenged our view of the role that protein motions play in light-harvesting processes. Several groups have ...
Development and validation of a simple high-performance liquid chromatography analytical method for simultaneous determination of phytosterols, cholesterol, and squalene in parenteral lipid emulsions.
A simple analytical method for simultaneous determination of phytosterols, cholesterol and squalene in lipid emulsions was developed owing to increased interest in their clinical effects. Method development was based on ...
Development and Validation of an HPLC-MS/MS Method for Pioglitazone from Nanocarriers Quantitation in Ex Vivo and In Vivo Ocular Tissues
Abstract: Pioglitazone (PGZ) is an oral anti-hyperglycemic agent, belongs to the class of thiazolidinediones, and is used for the treatment of diabetes mellitus type 2. In recent years, its anti-inflammatory activity has ...
