Universitat de Barcelona
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Política d’accés obert a la UB
Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.
ATP phosphoribosyltransferase, which catalyzes the first step of histidine biosynthesis, is regulated by a complex allosteric mechanism involving the regulatory protein HisZ and the catalytic subunit HisGS. HisZ enhances ...
Photosynthesis relies on highly organized pigment–protein complexes in order to store sunlight energy as biochemical energy. These complexes capture light with remarkable efficiency and are responsible for ultrafast charge ...
La utilización de la combinación a dosis fija de tramadol/dexketoprofeno en España y en otros países ha aumentado de forma considerable. La indicación terapéutica autorizada de este medicamento es el tratamiento sintomático ...
Objetivo: la actividad de los promotores y Comitésde ÉticadelaInvestigación con medicamentos haaumentado enlosúltimosaños.Elobjetivofuediseñaryvalidar2instrumentosparaanalizaryevaluarlacalidadformal dela hoja de información ...
The prevalence of elderly patients with chronic illnesses, associated polypharmacy and a high risk of functional and cognitive impairment has increased in recent</p><p>years. The care of Complex Chronic Patients (CCP) ...
Background and purpose: </strong>Clinical trials (CTs) aimed at vulnerable groups, such as patients with mental disorders, create ethical complexity. The patient information sheet (PIS) should provide all of the information ...
Introducción: En la temporada 2020-2021 se realizaron campañas mayores de vacunación antigripal, primordialmente en pacientes inmunocomprometidos y sus convivientes. Objetivos: Principal: determinar el impacto de la pandemia ...
Celiac disease (CD) is one of the most common gluten-related disorders. Although the only effective treatment is a strict gluten-free diet, doubts remain as to whether healthcare professionals take this restriction into ...
Objetivos: Conocer la composición cuantitativa de sodio en las formas farmacéuticas efervescentes y en soluciones de analgésicos, suplementos de calcio y mucolíticos utilizadas crónicamente; evaluar en qué proporción se ...
The main objective was to develop and validate a "Hospital Outpatients' Information Needs Questionnaire" (HOINQ). Secondly, to identify patients' preferred sources of information. Finally, to establish differences depending ...
Introduction The increase in elderly population has led to an associated increase in multiple pathologies, frailty, polypharmacy, healthcare costs, decreased quality of life and mortality. We designed an intervention based ...
Obtention of customized dosage forms is one of the main attractions of 3D printing in pharmaceuticals. In this sense, children are one of the groups within the population with a greater need for drug doses adapted to their ...
Rotavirus remains a major cause of severe acute gastroenteritisin infants worldwide. The suboptimal efficacy of current vaccines underscores the needfor alternative microbiome-based interventions, including postbiotics. ...
We present QM/MMPol-cLR<sup>3</sup>, a polarizable embedding quantum mechanics/molecular mechanics (QM/MM) framework that includes explicit, state-specific dispersion terms. This method enables a rigorous treatment of ...
Este estudio presenta la implementación y resultados de una prueba de Evaluación Clínica Objetiva Estructurada (ECOE) en la asignatura Farmacia Asistencial del grado de Farmacia de la Universitat de Barcelona durante los ...
Evaluar cómo el tipo de vaselina (líquida o sólida) influye en la estabilidad, liberación, permeación cutánea, retención y eficacia antiinflamatoria de formulaciones lipídicas tópicas con baricitinib (BCT), un inhibidor ...
Introduction: Polypharmacy, defined as the concomitant use of five or more medications, is common in older adults. Potentially inappropriate medications (PIMs) are drugs whose risks outweigh their potential benefits in ...
Background: Chronic graft-versus-host disease (cGVHD) is a rare and serious complication following allogeneic hematopoietic cell transplantation and a major cause of long-term morbidity and mortality. Approximately half ...
The pharmaceutical industry’s pursuit of enhanced product quality, regulatory compliance, and operational efficiency has catalyzed the integration of Artificial Intelligence (AI) into Ongoing Process Verification (OPV) ...
Multitarget compounds have emerged as promising drug candidates to cope with complex multifactorial diseases, like Alzheimer’s disease (AD). Most multitarget compounds are designed by linking two pharmacophores through a ...
