Farmàcia, Tecnologia Farmacèutica i Fisicoquímica: Recent submissions
Now showing items 61-80 of 664
Release of Ropinirole in Acrylate Transdermal Patches: Mutual Interactions Between Formulation Variables
The aim of this study is to evaluate the cooperative interactions between formulation variables of ropinirole transdermal patches and characterize the effects of drug loading and crystallinity, degree of ionization and ...
Endogenous Antioxidant Cocktail Loaded Hydrogel for Topical Wound Healing of Burns
Abstract: The main goal of this work is the study of the skin wound healing efficacy of an antioxidant cocktail consisting of vitamins A, D, E and the endogenous pineal hormone melatonin (MLT), with all of these loaded ...
Comparative Study of Donepezil-Loaded Formulations for the Treatment of Alzheimer's Disease by Nasal Administration
Abstract: Alzheimer's disease is characterized by a progressive deterioration of neurons resulting in a steady loss of cognitive functions and memory. Many treatments encounter the challenge of overcoming the blood-brain ...
Molecular simulations of globins: Exploring the relationship between structure, dynamics and function
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32392
Characterization of Ligand Binding in Human Serum Albumin from Atomistic Energy Transfer Simulations
Förster resonance energy transfer (FRET) is a key biophysical method for probing nanometer‑scale distances in biomolecular systems, but its direct application to protein–ligand complexes suffers from substantial biases due ...
Toward a unified modeling of environment and bridge-mediated contributions to electronic energy transfer: A fully polarizable QM/MM/PCM approach
Recent studies have unveiled the similar nature of solvent (screening) effects and bridge-mediated contributions to electronic energy transfer, both related to the bridge/solvent polarizability properties. Here, we exploit ...
Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges
World population growth and aging are posing unprecedented challenges in sus-taining the health of 9.1 billion people that will be occupying the planet by 2050.Although noncommunicable diseases such as cardiovascular and ...
Barómetro sobre competencias de la primera promoción de graduados en Farmacia (UB). Percepción del graduado ¿realmente ha contribuido la universidad?
Se ha llevado a cabo un estudio sobre las impresiones de una muestra de graduados de farmacia de la primera promoción (curso 2012/13) sobre competencias adquiridas y la influencia de la evaluación llevada a cabo en la ...
Clientes, espórtulas, parásitos
Comentaris sobre la costum del clients i espórtules a la societat romana amb la seva repercusió sobre la economia i la moralitat.
Evaluación del aprendizaje en asignaturas de máster con alumnos procedentes de diferentes grados.
Podeu consultar la Vuitena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/66524
Sex-Divergent Clinical Outcomes and Precision Medicine: An Important New Role for Institutional Review Boards and Research Ethics Committees
The efforts toward individualized medicine have constantly increased in an attempt to improve treatment options. These efforts have led to the development of small molecules which target specific molecular pathways involved ...
Surface functionalization of PLGA nanoparticles to increase transport across the BBB for Alzheimer's disease
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that accounts for about 60% of all diagnosed cases of dementia worldwide. Although there are currently several drugs marketed for its treatment, none are ...
MMPBSA decomposition of the binding energy throughout a molecular dynamics simulation of Amyloid-Beta (Aß10-35) aggregation
Recent experiments with amyloid-beta (Aß) peptides indicate that the formation of toxic oligomers may be an important contribution to the onset of Alzheimer's disease. The toxicity of Aß oligomers depend on their structure, ...
Mining Druggable Sites in Influenza A Hemagglutinin: Binding of the Pinanamine-Based Inhibitor M090
Assessing the binding mode of drug-like compounds is key in structure-based drug design. However, this may be challenged by factors such as the structural flexibility of the target protein. In this case, state-of-the-art ...
Análisis de sistemas bucoadhesivos
[spa]Objetivo: El objetivo de este estudio es el diseño de un parche bucoadhesivo para la administración transbucal de clorhidrato de doxepina utilizando diferentes polímeros así como la caracterización de dichos sistemas ...
Avaluació del curs de Dermofarmàcia per a la identificació d'accions de millora de la docència
Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/43352
Gram-negative bacteria outer and inner membrane models: insertion of cyclic cationic lipopeptides
Most Gram-negative bacteria are susceptible to polymyxin B (PxB), and development of resistance to this cationic lipopeptide is very rare. PxB mechanism of action involves interaction with both the outer membrane (OM) and ...
Drug-Related Problems Detected in Complex Chronic Patients by Community Pharmacists of Catalonia: Perception of the Person-Centred Approach Necessity
Community pharmacies are healthcare settings in which pharmacists are in an ideal position to carry out pharmaceutical care. The aim of this study was to analyse the number, type and groups of drugs that caused drug-related ...
Valoración experiencial del aprendizaje tras formación virtual.
[eng] An observable study on the behaviour in the laboratory of Pharmaceutical Technology II (pharmaceutical pilot plant), with two groups of students of 3rd course (proactive aptitude and valuation of the"knowledge to do ...
