Bioquímica i Biomedicina Molecular: Enviaments recents
Ara mostrant els elements 61-80 de 917
Nucleosome Dynamics: A new tool for the dynamic analysis of nucleosome positioning
We present Nucleosome Dynamics, a suite of programs integrated into a virtual research environment and created to define nucleosome architecture and dynamics from noisy experimental data. The package allows both the ...
Dopamine D1-histamine H3 receptor heteromers provide a selective link to the map-kinase signalling in gabaergic neurons of the direct striatal pathway
Home Current Issue Papers in Press Editors' Picks Minireviews Institution: Biblioteca de la Universitat de Barcelona Dopamine D1-histamine H3 receptor heteromers provide a selective link to the map-kinase signalling in ...
Unconnected body accrual of dietary lipid and protein in rats fed diets with different lipid and protein content
Scope: Eating large amounts of fat is usually associated with fat accumulation. However, different types of diets (not only lipids) elicit different metabolic responses. Methods and results: Male and female rats (10 week-old) ...
Formoterol and cancer wasting in rats: effects on muscle force and total physical activity
Cancer cachexia occurs in the majority of cancer patients before death, and it is responsible for the death of 22% of cancer patients. One of the most relevant characteristics of cachexia is that of asthenia, which reflects ...
Regulation of Expression of Cannabinoid CB2 and Serotonin 5HT1A Receptor Complexes by Cannabinoids in Animal Models of Hypoxia and in Oxygen/Glucose-Deprived Neurons
Background: Cannabidiol (CBD) is a phytocannabinoid with potential in one of the most prevalent syndromes occurring at birth, the hypoxia of the neonate. CBD targets a variety of proteins, cannabinoid CB2 and serotonin ...
Interleukin-19 impairment in active Crohn's disease patients
The exact function of interleukin-19 (IL-19) on immune response is poorly understood. In mice, IL-19 up-regulates TNFalpha and IL-6 expression and its deficiency increases susceptibility to DSS-induced colitis. In humans, ...
Neuregulin, an effector on mitochondria metabolism that preserves insulin sensitivity
Various external factors modulate the metabolic efficiency of mitochondria. This review focuses on the impact of the growth factor neuregulin and its ErbB receptors on mitochondria and their relationship with several ...
Integration of enzyme kinetic models and isotopomer distribution analysis for studies of in situ cell operation
A current trend in neuroscience research is the use of stable isotope tracers in order to address metabolic processes in vivo. The tracers produce a huge number of metabolite forms that differ according to the number and ...
Overexpression of S100A4 in human cancer cell lines resistant to methotrexate
Background: Methotrexate is a chemotherapeutic drug that is used in therapy of a wide variety of cancers. The efficiency of treatment with this drug is compromised by the appearance of resistance. Combination treatments ...
DFFR: A New Method for High-Throughput Recalibration of Automatic Force-Fields for Drugs
We present drug force-field recalibration (DFFR), a new method for refining of automatic force-fields used to represent small drugs in docking and molecular dynamics simulations. The method is based on fine-tuning of ...
Validation of miRNA-mRNA interactions by electrophoretic mobility shift assays
BACKGROUND: MicroRNAs are small non-coding RNAs involved in gene expression regulation by targeting specific regions in the 3[prime]-UTR of the mRNA of their target genes. This binding leads to a decrease in the protein ...
On the Mechanistic Perceptions of Consciousness: From Quantum Mechanics to Consciousness and Free Will and from David Bohm to Benjamin Libet
Biologists and biochemists have been reluctant to en-ter the realm of consciousness with real scientific meth-ods. One approach by Nobel laureate Francis Crick in hisbook "Astonishing Hypothesis: The Scientific Search for ...
Competency training of students of the Faculty of Chemistry of the University of Barcelona by conducting internal audits
This work deals with the competences and skills training of the students of the Faculty of Chemistry of the University of Barcelona (UB) through participation in internal audits at different laboratories in which different ...
Enfoque y creació de valor sostenible
En este artículo, el autor realiza un exhaustivo análisis de la actual situación de nuestro país en temas como la I+D, la innovación, la educación y la falta de espíritu emprendedor. También, pone de relieve las políticas ...
Quantitative analysis of rat adipose tissue cell recovery, and non-fat cell volume, in primary cell cultures.
Podeu consultar dades primàries associades a l'article a: http://hdl.handle.net/2445/102243
El drama de l'educació
La principal conclusió és que la possibilitat d'accés a la universitat està molt condicionada per l'origen social de l'estudiant. Concretament, conclouen que la probabilitat d'accedir a la universitat dels joves amb pares ...
Ghrelin and Cannabinoid Functional Interactions Mediated by Ghrelin/CB1 Receptor Heteromers That Are Upregulated in the Striatum From Offspring of Mice Under a High-Fat Diet
We have here assessed, using Δ9-tetrahydrocannabinol (Δ9-THC) for comparison, the effect of Δ9-tetrahydrocannabinolic acid (Δ9-THCA) and of Δ9-tetrahydrocannabivarin (Δ9-THCV) that is mediated by human versions of CB1, ...
CD4 expression decrease by antisense oligonucleotides. Inhibition of rat T CD4+ cell reactivity
In previous studies, we have demonstrated the inhibition of CD4 expression in rat lymphocytes treated with phorbol myristate acetate (PMA) by antisense oligonucleotides (AS-ODNs) directed against the AUG start region of ...
Coordination of mitochondrial and lysosomal homeostasis mitigates inflammation and muscle atrophy during aging
Sarcopenia is one of the main factors contributing to disability of aged people. Among the possible molecular determinants of sarcopenia, increasing evidences suggest that chronic inflammation contributes to its development. ...
Falta suport a la Universitat
S'ha lloat el sistema de recerca català obviant que la major part de la recerca de Catalunya es fa a les universitats i, si ens fixem en la recerca en l'àmbit de salut, de gran nivell, haurem d'anar al conjunt format per ...
