Universitat de Barcelona
2012-10-04T10:37:46Z
2012-10-04T10:37:46Z
2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393
The c-Jun N-terminal kinases (JNK) are members of the MAPK family and can be activated by different stimuli such as cellular stress, heat shock and ultra-violet irradiation. JNKs have different physiological functions and they have been linked to apoptosis in different cell types. Therefore, the JNK signalling pathway is an important target to prevent cell death. In the present chapter, the role of JNKs in neurodegenerative diseases will be discussed, as well as the pharmacological compounds that inhibit this signalling pathway as therapeutic intervention to prevent neuronal death.
Chapter or part of a book
Published version
English
Farmacologia; Malalties neurodegeneratives; Pharmacology; Neurodegenerative Diseases
Transworld Research Network
Reproducció del capítol 2 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=131
Recent Advances in Pharmaceutical Sciences II, 2012, Editor: Diego Muñoz-Torrero, Diego Haro and Joan Vallès, Chapter 2, p. 15-28.
http://hdl.handle.net/2445/32393
(c) Transworld Research Network, 2012
