dc.contributor.author
Subirós Funosas, Ramon
dc.contributor.author
Cheuk Lam Ho, Vivian
dc.contributor.author
Barth, Nicole D.
dc.contributor.author
Mendive Tapia, Lorena
dc.contributor.author
Pappalardo, Morena
dc.contributor.author
Barril Alonso, Xavier
dc.contributor.author
Ma, Ruoyu
dc.contributor.author
Zhang, Cheng-Bin
dc.contributor.author
Qian, Bin-Zhi
dc.contributor.author
Sintes Marcos, Miquel
dc.contributor.author
Ghashghaei, Ouldouz
dc.contributor.author
Lavilla Grífols, Rodolfo
dc.contributor.author
Vendrell, Marc
dc.date.issued
2021-07-22T11:47:36Z
dc.date.issued
2021-07-22T11:47:36Z
dc.date.issued
2020-01-20
dc.date.issued
2021-07-22T11:47:36Z
dc.identifier
https://hdl.handle.net/2445/179354
dc.description.abstract
Keratin 1 (KRT1) is overexpressed in squamous carcinomas and associated with aggressive pathologies in breast cancer. Herein we report the design and preparation of the first Trp-based red fluorogenic amino acid, which is synthetically accessible in a few steps and displays excellent photophysical properties, and its application in a minimally-disruptive labelling strategy to prepare a new fluorogenic cyclopeptide for imaging of KRT1+ cells in whole intact tumour tissues.
dc.format
application/pdf
dc.publisher
Royal Society of Chemistry
dc.relation
Reproducció del document publicat a: https://doi.org/10.1039/C9SC05558D
dc.relation
Chemical Science, 2020, vol. 11, p. 1368-1374
dc.relation
https://doi.org/10.1039/C9SC05558D
dc.relation
info:eu-repo/grantAgreement/EC/H2020/771443/EU//DYNAFLUORS
dc.relation
info:eu-repo/grantAgreement/EC/H2020/716379/EU//MetResistance
dc.rights
cc-by (c) Subirós Funosas, Ramon et al., 2020
dc.rights
http://creativecommons.org/licenses/by/3.0/es/
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.title
Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
