dc.contributor.author
Bennasar Fèlix, M. Lluïsa
dc.contributor.author
Zulaica Gallego, Ester
dc.contributor.author
Solé Arjó, Daniel
dc.contributor.author
Alonso Serrano, Sandra
dc.date.issued
2020-06-04T11:38:03Z
dc.date.issued
2020-06-04T11:38:03Z
dc.date.issued
2012-06-17
dc.date.issued
2020-06-04T11:38:03Z
dc.identifier
https://hdl.handle.net/2445/164274
dc.description.abstract
A chemoselective indole-templated ring-closing metathesis is used to assemble the cyclohepta[b]indole substructure of the indole alkaloid ervitsine. A subsequent intramolecular Heck coupling of the resulting alkene functionality with an amino-tethered vinyl halide accomplishes the closure of the unique 2- azabicyclo[4.3.1]decane framework of the alkaloid with concomitant incorporation of the exocyclic Eethylidene substituent.
dc.format
application/pdf
dc.publisher
Elsevier B.V.
dc.relation
Versió postprint del document publicat a:
dc.relation
Tetrahedron, 2012, vol. 68, num. 24, p. 4641-4648
dc.rights
(c) Elsevier B.V., 2012
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Metàtesi (Química)
dc.subject
Reaccions químiques
dc.subject
Productes naturals
dc.subject
Síntesi orgànica
dc.subject
Metathesis (Chemistry)
dc.subject
Chemical reactions
dc.subject
Natural products
dc.subject
Organic synthesis
dc.title
Sequential ring-closing metathesis-vinyl halide Heck cyclization reactions: access to the tetracyclic ring system of ervitsine
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
