2019-05-06T13:51:42Z
2019-05-06T13:51:42Z
2016-02
2019-05-06T13:51:42Z
The rapid increase of drug resistant bacteria makes necessary the development of new antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising alternative to conventional antimicrobial compounds given that they can be prepared from renewable raw materials. In this review, we discuss the structural features that promote antimicrobial activity of amino acid-based surfactants. Monocatenary, dicatenary and gemini surfactants that contain different amino acids on the polar head and show activity against bacteria are revised. The synthesis and basic physico-chemical properties have also been included.
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Agents tensioactius; Tecnologia farmacèutica; Fórmules magistrals; Agents antiinfecciosos; Microbiologia; Aminoàcids; Toxicitat dels medicaments; Surface active agents; Pharmaceutical technology; Medical formularies; Anti-infective agents; Microbiology; Amino acids; Drug toxicity
Elsevier
Versió postprint del document publicat a: https://doi.org/10.1016/j.cis.2015.11.007
Advances in Colloid and Interface Science, 2016, vol. 228, p. 17-39
https://doi.org/10.1016/j.cis.2015.11.007
cc-by-nc-nd (c) Elsevier, 2016
http://creativecommons.org/licenses/by-nc-nd/3.0/es