Amino-acid-based surfactants: New antimicrobial agents

Abstract

The rapid increase of drug resistant bacteria makes necessary the development of new antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising alternative to conventional antimicrobial compounds given that they can be prepared from renewable raw materials. In this review, we discuss the structural features that promote antimicrobial activity of amino acid-based surfactants. Monocatenary, dicatenary and gemini surfactants that contain different amino acids on the polar head and show activity against bacteria are revised. The synthesis and basic physico-chemical properties have also been included.

Document Type

Article


Accepted version

Language

English

Publisher

Elsevier

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Versió postprint del document publicat a: https://doi.org/10.1016/j.cis.2015.11.007

Advances in Colloid and Interface Science, 2016, vol. 228, p. 17-39

https://doi.org/10.1016/j.cis.2015.11.007

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Rights

cc-by-nc-nd (c) Elsevier, 2016

http://creativecommons.org/licenses/by-nc-nd/3.0/es

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