dc.contributor.author
Amat Tusón, Mercedes
dc.contributor.author
Fabregat, Robert
dc.contributor.author
Griera Farres, Rosa
dc.contributor.author
Bosch Cartes, Joan
dc.date.issued
2017-03-10T15:24:51Z
dc.date.issued
2017-03-10T15:24:51Z
dc.date.issued
2009-02-20
dc.date.issued
2017-03-10T15:24:51Z
dc.identifier
https://hdl.handle.net/2445/108263
dc.description.abstract
A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of 2-substituted 6-oxocyclohexenepropionates 2 with (R)-phenylglycinol, the stereoselective hydrogenation of the resulting unsaturated tricyclic lactams, and the stereoselective reductive cleavage of the oxazolidine ring.
dc.format
application/pdf
dc.publisher
American Chemical Society
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1021/jo802587h.
dc.relation
Journal of Organic Chemistry, 2009, vol. 74, num. 4, p. 1794-1797
dc.relation
https://doi.org/10.1021/jo802587h.
dc.rights
(c) American Chemical Society , 2009
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Síntesi orgànica
dc.subject
Reacció d'oxidació-reducció
dc.subject
Quinolone antibacterial agents
dc.subject
Organic synthesis
dc.subject
Oxidation-reduction reaction
dc.title
A General Synthetic Route to Enantiopure 5-Substituted cis-Decahydroquinolines
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
