Química Inorgànica i Orgànica: Recent submissions
Now showing items 61-80 of 978
Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides
The MaxPHOX-Ir catalyst system provided the highest selectivity ever reported for the redn. of cyclic enamides derived from α- and β-tetralones. This result indicates that iridium catalysts are also proficient in reducing ...
New Visible-Light-Sensitive Dicyanocoumarin- andCOUPY-Based Caging Groups with ImprovedPhotolytic Efficiency
Photolabile protecting groups (PPGs), also known as caging groups, are valuable tools in photopharmacology. They enable precise control over the release of bioactive compounds from the corresponding caged compounds at a ...
Intramolecular fuzzy interactions involving intrinsically disordered domains
Structural disorder is an essential ingredient for function in many proteins and protein complexes. Fuzzy complexes describe the many instances where disorder is maintained as a critical element of protein interactions. ...
An overview of nanomedicines for neuron targeting
Medical treatments of neuron-related disorders are limited due to the difficulty of targeting brain cells. Major drawbacks are the presence of the blood-brain barrier and the lack of specificity of the drugs for the diseased ...
Helix fraying and lipid-dependent structure of a short amphipathic membrane-bound peptide revealed by solid-state NMR
The amphipathic a-helical peptide KIA14 [(KIAGKIA)(2)-NH2] was studied in membranes using circular dichroism and solid-state NMR spectroscopy to obtain global as well as local structural information. By analyzing H-2 NMR ...
Single molecule fluorescence reveals dimerization of myristoylated Src N-terminal region on supported lipid bilayers
The proto-oncogene tyrosine-protein kinase Src is a key ele- ment of signaling cascades involved in the invasive and meta- stasis-forming capacity of cancer cells. While membrane ty- rosine-kinase receptors are known to ...
Embedding catalytic nanoparticles inside mesoporous structures with controlled porosity: Au@TiO2
The ability to produce catalytic nanoparticles with controlled properties is key to developing and producing heterogeneous catalysts with optimized activity and selectivity. No less important is to maximize the nanoparticle ...
Carboxylato bridging Cu(II) coordination polymer: Structure, magnetism and catalytic reduction of nitrophenols
The 1D coordination polymer, [Cu 2 ( μ2 -OH) 2 (DABA) 2 ] n ( 1 ), (HDABA = 4-Diallylamino-benzoic acid) is characterized by Single crystal X-Ray diffraction analysis. The structure switches to a 2D geometry by hy- drogen ...
Case history of porphyrin J-aggregates: a personal point of view
The formation and structure of the title aggregates are paradigms of the self-assembly of amphiphilic molecular building blocks in supramolecular chemistry. This review summarizes the research in the University of Barcelona ...
A novel nucleophilic approach to 1-alkyladenosines. A two-step synthesis of [1-N-15] adenosine from inosine
A novel ANRORC mechanism in the reaction of 1-(2,4-dinitrobenzenesulfonyl)inosines with amines has allowed the preparation of 1-alkyladenosines and [1-15N]adenosines in a straightforward way from inosines.
Molecular basis of the selective binding of MDMA enantiomers to the Alpha4Beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies
The α4β2 nicotinic acetylcholine receptor (nAChR) is a molecular target of 3,4-methylenedioxymethamphetamine (MDMA), a synthetic drug also known as ecstasy, and it modulates the MDMA-mediated reinforcing properties. However, ...
Exploring Structure-Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates
Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with operability under hypoxic conditions remain ...
[UF6](2-): A molecular hexafluorido actinide(IV) complex with compensating spin and orbital magnetic moments
The first structurally characterized hexafluorido complex of a tetravalent actinide ion, the [UF6]2- anion, is reported in the (NEt4)2[UF6]2H2O salt (1). The weak magnetic response of 1 results from both U(IV) spin and ...
Monocyclopentadienyltitanium(III) Complexes with Hydridoborato Ligands
The synthesis, properties and reactivity of monocyclopentadienyltitanium(III) complexes stabilized by hydridoborato (BH3R)‒ ligands are reported. The reactions of the titanium(IV) trichlorides [Ti(h5-C5H5-nMen)Cl3] with ...
Novel Zn(II) coordination polymers based on the natural molecule bisdemethoxycurcumin
This article introduces a new family of coordination polymers (CPs) that contains a renewable curcumin derivative, the bisdemethoxycurcumin (BDMC), coordinated to Zn(II) centers. The reaction between BDMC and zinc acetate, ...
A green light-triggerable RGD peptide for photocontrolled targeted drug delivery: synthesis and photolysis studies
We describe for the first time the synthesis and photochemical properties of a coumarin-caged cyclic RGD peptide and demonstrate that uncaging can be efficiently performed with biologically compatible green light. This was ...
Polynuclear Fe(II) complexes: Di/trinuclear molecules and coordination networks
We review here the recent progress made in the synthesis of spin crossover (SCO) Fe(II) coordination complexes with two or three metal atoms, as well as coordination polymers, with the main focus on that in the last five ...
A Nanoencapsulated Ir(III)-Phthalocyanine Conjugate as a Promising Photodynamic Therapy Anticancer Agent
Despite the potential of photodynamic therapy (PDT) in cancer treatment, the development of efficient and photostable photosensitizing molecules that operate at long wavelengths of light has become a major hurdle. Here, ...
Una nova aportació en la docència de la química a la frontera secundària-universitat: Les jornades 'Fem química al laboratori' de la Facultat de Química de la Universitat de Barcelona
[cat] L'any 2002 un grup de professors de la Facultat de Química de la Universitat de Barcelona va posar en marxa «Fem química al laboratori», una nova activitat docent, amb l'objectiu de contribuir a la formació dels ...
Synthesis, characterization, solution behavior and theoretical studies of Pd(II) Allyl Complexes with 2-Phenyl-3H-indoles as ligands
The study of the reactivity of three 2-phenyl-3H-indole ligands of general formulae C8H3N-2-(C6H4-4-R1)-3-NOMe-5-R2 (1) [with R1 = H, R2 = OMe (a); R1 = R2 = H (b) or R1 = Cl, R2 = H (c)] with [Pd(η3-1-R3C3H4)(μ-Cl)]2 (R3 ...
