Química Inorgànica i Orgànica: Enviaments recents
Ara mostrant els elements 1-20 de 1011
Hydrophilic Janus Micelles from an ABC Triblock Copolymer
We describe the creation of an amphiphilic triblock copolymer that drives lateral phase separation within micelle coronas. The design combines a hydrophobic poly(lactide) (PLA) core ‑forming block with two distinct hydrophilic ...
Transferrin receptor 1-targeted polymersomes therapy for colorectal cancer
Colorectal cancer (CRC) ranks among the most common cancers and is the second leading cause of cancer-related</p><p>deaths. The high mortality associated with CRC is attributed mainly to difficulties in early detection and ...
Decoding the Conformation of Polylactic Acid in Block Copolymer Micelles
Understanding how molecular features dictate the self-assembly of amphiphilic block copolymers into well-defined nanostructures is essential for the rational design of advanced soft materials. However, the large number of ...
No Switching Cooperativity between Coordinated Azo Ligands on Complexes Having {M<sup>II</sup>(phosphane-κ<sup>2</sup><em>P</em>)}<sup>2+</sup> (M = Pd, Pt) Scaffolds
A series of square-planar palladium and platinum compounds with cis-blocking phosphanes and terminal azobenzene ligands ${[M(dppp)-(azo)_{2}] (OTf)_{2} (azo = CN(C_{6}H_{4})-N = N-(C_{6}H_{4})CN (iso-cyano), CN(C_{6}H_{4})-N ...
Environment-responsive Pt(II) complexes boost aggregation-enhanced emission and singlet oxygen production
Here, we introduce an environment-tuning strategy to simultaneously boost aggregation-enhanced emission (AEE) and singlet oxygen (1O2) generation in PEGylated platinum(II) pyridyl complexes. Different amphiphilic Pt(II) ...
Lighting the Way: Supramolecular Luminescent Chemosensors for a Safer Environment
In this Guest Editorial, the special issue of ChemistryEurope on supramolecular luminescent chemosensors (LCs) is presented, showcasing selected contributions from members of the COST Action LUCES (CA22131). LCs are a ...
Environment-responsive Pt(II) complexes boost aggregation-enhanced emission and singlet oxygen production
Here, we introduce an environment-tuning strategy to simultaneously boost aggregation-enhanced emission (AEE) and singlet oxygen (1O2) generation in PEGylated platinum(II) pyridyl complexes. Different amphiphilic Pt(II) ...
Novel Heteroleptic Iridium(III) Complexes Containing COUBPY Ligands for Effective Photoinduction of Ferroptosis for Cancer Therapy
Ferroptosis, a recently described form of regulated, nonapoptotic cell death mechanism, presents significant potential for cancer treatment, particularly when combined with photodynamic therapy (PDT). In this study, we ...
Comparative Magnetic Studies in the Solid State and Solution of Two Isostructural 1D Coordination Polymers Containing Co<sup>II</sup>/Ni<sup>II</sup>-Curcuminoid Moieties
Two novel 1D coordination chains containing the curcuminoid (CCMoid) ligand 9Accm have been characterized: [CoII(9Accm)2(4,4´-bpy)]n (1) and [NiII(9Accm)2(4,4´-bpy)]n (2). The two compoundsweresynthesizedbysolvothermalandmicrowave ...
Multi-Modal Constrastive Learning for Chemical Structure Elucidation with VibraCLIP
Identifying molecular structures from vibrational spectra is central to chemical analysis but remains challenging due to spectral ambiguity and the limitations of single-modality methods. While deep learning has advanced ...
Gold(I) organometallic supramolecular assemblies. Luminescence and applications
This chapter explores the fascinating domain of gold(I) organometallic supramolecular assemblies, emphasizing their luminescence properties and versatile applications. Gold(I) complexes have shown remarkable potential due ...
Shortcut to Highly Fluorescent Perylene Derivatives: FromFluoranthene Fissure-Coupling to Late-Stage Aromatic Extension
<p>Access to extended perylene-based nanographenes (NGs) is severely limited and involves tedious multi-step synthetic procedures. Here a two-step synthesis shortcut to highly soluble, bent, and extended perylene-based NGs ...
Novel synthetic polymyxins kill Gram-positive bacteria
Background: Staphylococcus aureus, including 'superbug' MRSA, is a major cause of nosocomial infections. In the European Union, up to 171 200 new nosocomial MRSA infections are acquired annually, and in the USA S. aureus ...
Insights into type I photoreactivity of cyclometalated iridium(III) and ruthenium(II) photosensitizers
Photodynamic therapy (PDT) is a light-activated treatment that relies on the generation of cytotoxic reactive oxygen species (ROS). While most clinically approved photosensitizers (PSs) operate through a type II mechanism—based ...
A Cathepsin B-Triggered CO-Releasing Molecule with a Non-Toxic Metal Core for Targeted Tumor Delivery
Carbon monoxide (CO) has shown therapeutic potential across various diseases, including cancer. To enable controlled delivery, many CO-releasing molecules (CORMs) have been developed. However, their clinical translation ...
Transfer learning based on atomic feature extraction for the prediction of experimental <sup>13</sup>C chemical shifts
Forecasting experimental chemical shifts of organic compounds is a long-standing challenge in organic chemistry. Recent advances in machine learning (ML) have led to routines that surpass the accuracy of ab initio Density ...
Colistin-loaded biodegradable nanoparticles as a promising antibacterial medication to reduce colistin-induced toxicity
Infectious diseases cause mortality rates over 17 million people per year. Among them, bacterial infections constitute one of the major causes. Pneumonia and nosocomial infections are the most severe bacterial infections. ...
Rhodium(I) Complexes with a n1- Fluorenyl, <em>P</em>-Phosphanyl-Phosphorane Ligand
The first example of a P-phosphanylphosphorane, Flu�PCy2−PCy2 (L2; Flu = 9-fluorenyl), has been easily prepared by P-phosphination of lithiated 9-dicyclohexylphosphinofluorene (FluPCy2, L0) with chlorodicyclohexylphosphane. ...
Self-assembly of a supramolecular spin-crossover tetrahedron
Spin-crossover (SCO) compounds are fascinating switchable materials with great potential for the development of novel technological devices. These coordination complexes exhibit metal ions with two possible electronic ...
Time-optimal control of a solid-state spin amidst dynamical quantum wind
Time-optimal control holds promise across the full spectrum of quantum technologies, where the rapid generation of unitary gates and state transformations is crucial to mitigate decoherence effects. In practical scenarios, ...
