Patologia i Terapèutica Experimental: Enviaments recents
Ara mostrant els elements 21-40 de 1057
Transforming growth factor -α expression in rat experimental hepatocarcinogenesis
Growth factors in general and transforming growth factor-alpha in particular have been related to cell proliferation and cell differentiation. This study was designed to clarify the distribution pattem of TGF-alpha in ...
SPARC triggers a cell-autonomous program of synapse elimination
Elimination of the excess synaptic contacts established in the early stages of neuronal development is required to refine the function of neuronal circuits. Here we investigate whether secreted protein acidic and rich in ...
Prognostic value of replication errors on chromosomes 2p and 3p in non-small-cell lung cancer
As chromosomes 2p and 3p are frequent targets for genomic instability in lung cancer, we have addressed whether alterations of simple (CA)n DNA repeats occur in non-small-cell lung cancer (NSCLC) at early stages. We have ...
Implementing reflective multicriteria decision analysis (MCDA) to assess orphan drugs value in the Catalan Health Service (CatSalut)
Background: orphan medicines show some characteristics that hinder the evaluation of their clinical added value. The often low level of evidence available for orphan drugs, together with a high budget impact and an incremental ...
Functional approach using intraoperative brain mapping and neurophysiological monitoring for the surgical treatment of brain metastases in the central region
Objective: Brain metastases are the most frequent intracranial malignant tumor in adults. Surgical intervention for metastases in eloquent areas remains controversial and challenging. Even when metastases are not infiltrating ...
Histomorphometric analysis of osseointegrated grade V titanium mini transitional implants inEdentulous mandible by backscattered scanning electron microscopy (BS-SEM)
The purpose of this study is to assess the use of grade V titanium mini transitional implants(MTIs) immediately loaded by a temporary overdenture. For this, a histomorphometric analysisof the bone area fraction occupancy ...
Proteins influencing foam formation in wine and beer: the role of yeast
This review focuses on the role of proteins in the production and maintenance of foam in both sparkling wines and beer. The quality of the foam in beer but especially in sparkling wines depends, among other factors, on the ...
Acinetobacter sp: importància com a patogen nosocomial en l'actualitat
El gènere Acinetobacter està format per bacils gramnegatius immòbils àmpliament distribuïts en la natura. Des de la seva descripció, els membres d'aquest gènere han patit nombrosos canvis taxonòmics, en part a causa de ...
Kinematic and Kinetic Adaptations to Step Cadence ModulationDuringWalking in Healthy Adults
Walking cadence is commonly adjusted in sport and rehabilitation, yet itseffects on spatiotemporal gait parameters and regional plantar pressure distribution undercontrolled speed conditions remain incompletely characterized. ...
Cord blood-derived neuronal cells by ectopic expression of SOX2 and c-MYC
The finding that certain somatic cells can be directly converted into cells of other lineages by the delivery of specific sets of transcrip- tion factors paves the way to novel therapeutic applications. Here we show that ...
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices
Electron microscopy can resolve synapse ultrastructure with nanometer precision, but the capture of time-resolved, activity-dependent synaptic membrane-trafficking events has remained challenging, particularly in functionally ...
All-optical electrophysiology for high-throughput functional characterization of a human iPSC-Derived motor neuron model of ALS
Human induced pluripotent stem cell (iPSC)-derived neurons are an attractive substrate for modeling disease, yet the heterogeneity of these cultures presents a challenge for functional characterization by manual patch-clamp ...
Enfermedad neuromuscular oculocraniosomática de Kearns Sayre: a propósito de tres casos
Se describen tres pacientes de 9. 7 y 28 años, afectos del síndrome neuromuscular oculocraneosomático de Kearns-Sayre. A dichos enfermos se les ha practicado T.C. cerebral E.R.G.. potenciales evocados visuales, acústicos ...
Sonic hedgehog promotes generation and maintenance of human forebrain Olig2 progenitors
Function of oligodendrocytes (OLs), myelin forming cells in the CNS, is disrupted in demyelinating diseases such as periventricular leukomalacia or multiple sclerosis. It is, thus, important to better understand factors ...
The lateral fibulotalocalcaneal ligament complex: an ankle stabilizing isometric structure
Purpose: Ankle lateral collateral ligament complex has been the focus of multiple studies. However, there are no specific descriptions of how these ligaments are connected to each other as part of the same complex. The aim ...
Disposición del sistema trabecular esclero-corneal en fetos humanos
Disposición del sistema trabecular esclero-córneal en fetos humanos: en el presente trabajo mediante el estudio con el microscopio óptico y de barrido de ojos de 20 fetos humanos de 33 a 326 mm. (7 a 36 semanas de gestación), ...
Incidence and molecular typing of Mycobacterium kansasii in a defined geographical area in Catalonia, Spain
A retrospective population-based study was conducted between January 1990 and December 1998 to investigate the incidence of Mycobacterium kansasii disease and the heterogeneity of the isolates in a well-defined geographical ...
Experimental study on radioactive pathways of hypodermically injected technetium-99m
The objective of this study was to investigate the biological substrate of radioactive pathways of migration of hypodermically injected 99mTc into points of low electrical resistance. Sixteen anesthetized adult male beagles ...
Laboratory diagnosis of brucellosis in a rural endemic area in northeastern Spain
Sera obtained from 62 patients from four mountain counties in Catalonia (Northeastern Spain), in whom brucellosis had been diagnosed on the basis of clinical evidence and/or personal history, were analyzed using the rose ...
Utilització de l'e-Learning en Farmacologia. Metodologia emprada per implementar-lo.
El nostre objectiu docent és aconseguir una docència funcional. L'alumne ha de poder utilitzar els coneixements adquirits en la seva professió. Enlloc de retenir informació que romangui inert o s'oblidi, ha de realitzar ...
