Institut de Bioenginyeria de Catalunya (IBEC)

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Els materials de recerca de la Universitat de Barcelona (UB) a RECERCAT s'obtenen de les col·leccions de Recerca del Dipòsit Digital de la UB.
Si sou membre de la UB i esteu interessat a publicar materials de recerca contacteu amb dipositdigital@ub.edu o consulteu les indicacions .

Política d’accés obert a la UB


Publicacions en accés obert derivades de l'activitat investigadora del professorat de la Universitat de Barcelona.

Enviaments recents

Llista ítems afegits recenment

Mapping mechanical stress in curved epithelia of designed size and shape 

Marín Llauradó, Ariadna; Kale, Sohan; Ouzeri, Adam; Golde, Tom; Sunyer Borrell, Raimon; Torres Sánchez, Alejandro; Latorre Ibars, Ernest; Gómez González, Manuel; Roca-Cusachs Soulere, Pere; Arroyo, Marino; Trepat Guixer, Xavier (Data de publicació: 2026-03-11)

The function of organs such as lungs, kidneys and mammary glands relies on the three-dimensional geometry of their epithelium. To adopt shapes such as spheres, tubes and ellipsoids, epithelia generate mechanical stresses ...

Who arrived first? Priority effects on Candida albicans and Pseudomonas aeruginosa dual biofilms 

Arévalo Jaimes, Betsy Verónica; Admella, Joana; Torrents Serra, Eduard (Data de publicació: 2026-03-02)

Historical processes in community assembly, such as species arrival order, influence interactions, causing priority effects. Candida albicans and Pseudomonas aeruginosa often co-occur in biofilm-based infections of the ...

Improving neuroblastoma therapy with a new p53 family-activating agent 

Almeida, Joana; Resende, Diana I. S. P.; Silva, R.; Villasante Bermejo, Aranzazu; Murphy, Catherine; Zingales, Veronica; Palmeira, Andreia; Skoda, Jan; Broso, Francesca; Vadivellu, Aiswariya; Oliveira, Paula A.; Reis, Salette; Nunes, Claudia; Loh, Amos H.P.; Ferreira, Joana Margarida; Martins, Eduarda P.; Costa, Bruno M.; Inga, Alberto; Samitier i Martí, Josep; Sousa, Emilia P.; Saraiva, Lucília (Data de publicació: 2026-02-27)

Neuroblastoma (NB) is among the most common malignancies in children and represents a therapeutic challenge in pediatric oncology. p53 family proteins play a critical role in protecting cells from genomic instability and ...

The minimal chemotactic cell 

Battaglia, Giuseppe; Borges Fernandes, Barbara; Apriceno, Azzurra; Arango-Restrepo, Andrés; Almadhi, Safa; Ghosh, Subhadip; Forth, Joe; López-Alonso, Jorge Pedro; Ubarretxena-Belandia, Iban; Rubi, José Miguel; Ruiz-Perez, Lorena; Williams, Ian (Data de publicació: 2025-11-28)

The movement of cells and microorganisms in response to chemical gradients (chemotaxis) has played an essential role in the evolution of many biological processes. Cellular navigation works via the holistic assembly of ...

Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport 

Gong, Qiyong; Tian, Xiaohe; Battaglia, Giuseppe; Chen, Junyang; Xiang, Pan; Duro-Castano, Aroa; Cai, Huawei; Guo, Bin; Liu, Xiqin; Yu, Yifan; Lui, Su; Luo, Kui; Ke, Bowen; Ruiz-Perez, Lorena (Data de publicació: 2025-11-28)

The blood‒brain barrier (BBB) is a highly selective permeability barrier that safeguards the central nervous system (CNS) from potentially harmful substances while regulating the transport of essential molecules. Its ...

Thermoplasmonic Polymersome Membranes by In Situ Synthesis 

Barbieri, Valentino; González Colsa, Javier; Matias, Diana; Duro-Castano, Aroa; Thapa, Anshu; Ruiz-Perez, Lorena; Albella, Pablo; Volpe, Giorgio; Battaglia, Giuseppe (Data de publicació: 2025-11-14)

Thermoplasmonic nanoparticles, known for releasing heat upon illumination, find diverse applications in catalysis, optics, and biomedicine. Incorporating plasmonic metals within organic vesicle membranes can lead to the ...

Ferrofluid-based bioink for 3d printed skeletal muscle tissues with enhanced force and magnetic response 

Fuentes Llanos, Judith; Guix Noguera, Maria; Cenev, Zoran M.; Bakenecker, Anna; Ruiz González, Noelia; Beaune, Grégory; Timonen, Jaakko V. I.; Sánchez Ordóñez, Samuel; Magdanz, Veronika (Data de publicació: 2025-08-01)

3D printing has emerged as a transformative technology in several manufacturing processes, being of particular interest in biomedical research for allowing the creation of 3D structures that mimic native tissues. The process ...

Microfluidic model of the alternative vasculature in neuroblastoma 

Villasante Bermejo, Aranzazu; López Martínez, Maria José; Quiñonero López, Gema; García Lizarribar, Andrea; Peng, Xiaofeng; Samitier i Martí, Josep (Data de publicació: 2025-02-13)

Neuroblastoma (NB) is a highly vascularized pediatric tumor arising from undifferentiated neural crest cells early in life, exhibiting both traditional endothelial-cell-driven vasculature and an intriguing alternative ...

The multivalency game ruling the biology of immunity 

Aiassa, Lara; Battaglia, Giuseppe; Rizzello, Loris (Data de publicació: 2024-02-13)

Macrophages play a crucial role in our immune system, preserving tissue health and defending against harmful pathogens. This article examines the diversity of macrophages influenced by tissue-specific functions and ...

Flagellar Propulsion of Sperm Cells Against a Time-Periodic Interaction Force 

Wang, Zihan; Klingner, Anke; Magdanz, Veronika; Hoppenreijs, Merijn W; Misra, Sarthak; Khalil, Islam S M (Data de publicació: 2023-05-23)

Sperm cells undergo complex interactions with external environments, such as a solid-boundary, fluid flow, as well as other cells before arriving at the fertilization site. The interaction with the oviductal epithelium, ...

Mycobacterial surface characters remodeled by growth conditions drive different tumor-infiltrating cells and systemic IFN-gamma/IL-17 release in bladder cancer treatment 

Guallar Garrido, Sandra; Campo Pérez, Victor; Pérez Trujillo, Miriam; Cabrera, Cecilia; Senserrich, Jordi; Sánchez Chardi, Alejandro; Rabanal Prados, Rosa Ma. (Rosa Maria); Gómez Mora, Elisabet; Noguera Ortega, Estela; Luquin, Marina; Julian, Esther (Data de publicació: 2022-04-06)

The mechanism of action of intravesical Mycobacterium bovis BCG immunotherapy treatment for bladder cancer is not completely known, leading to misinterpretation of BCG-unresponsive patients, who have scarce further therapeutic ...

Ionic Species Affect the Self-Propulsion of Urease-Powered Micromotors 

Andres, Xavier; Arqué, Xavier; Mestre, Rafael; Ciraulo, Bernard; Ortega Arroyo, Jaime; Quidant, Romain; Patiño, Tania; Sanchez Ordoñez, Samuel (Data de publicació: 2022-07-18)

Enzyme-powered motors self-propel through the catalysis of in situ bioavailable fuels, which makes them excellent candidates for biomedical applications. However, fundamental issues like their motion in biological fluids ...

In silico antibody engineering for SARS-CoV-2 detection 

Martí Ballesté, Dídac; Martin Martinez, Eduard; Torras Costa, Joan; Bertran Cànovas, Òscar; Turon, Pau; Alemán Llanso, Carlos (Data de publicació: 2022-01-04)

Engineered immunoglobulin-G molecules (IgGs) are of wide interest for the development of detection elements in protein-based biosensors with clinical applications. The strategy usually employed for the de novo design of ...

Enhanced monitoring of sleep position in sleep apnea patients: Smartphone triaxial accelerometry compared with video-validated position from polysomnography 

Ferrer Lluis, Ignasi; Castillo Escario, Yolanda; Montserrat, Josep Maria; Jané, Raimon (Data de publicació: 2022-06-01)

Poor sleep quality is a risk factor for multiple mental, cardiovascular, and cerebrovascular diseases. Certain sleep positions or excessive position changes can be related to some diseases and poor sleep quality. Nevertheless, ...

Photo-BQCA: Positive Allosteric Modulators Enabling Optical Control of the M1 Receptor 

Gerwe, Hubert; Schaller, Eva; Sortino, Rosalba; Opar, Ekin; Martinez Tambella, Joaquin; Bermudez, Marcel; Lane, J Robert; Gorostiza Langa, Pablo Ignacio; Decker, Michael (Data de publicació: 2025-01-09)

The field of G protein-coupled receptor (GPCR) research has greatly benefited from the spatiotemporal resolution provided by light controllable, i.e., photoswitchable ligands. Most of the developed tools have targeted the ...

Islet-on-a-chip for the study of pancreatic β-cell function 

Ramón Azcón, Javier; Rodríguez Comas, Júlia (Data de publicació: 2022-02-01)

Diabetes mellitus is a significant public health problem worldwide. It encompasses a group of chronic disorders characterized by hyperglycemia, resulting from pancreatic islet dysfunction or as a consequence of insulin-producing ...

Drug-Loaded IRONSperm clusters: modeling, wireless actuation, and ultrasound imaging 

Middelhoek, Kaz I N A; Magdanz, Veronika; Abelmann, Leon; Khalil, Islam S M (Data de publicació: 2022-09-20)

Individual biohybrid microrobots have the potential to perform biomedical in vivo tasks such as remote-controlled drug and cell delivery and minimally invasive surgery. This work demonstrates the formation of biohybrid ...

Genome editing in human pluripotent stem cells: a systematic approach unrevealing pancreas development and disease 

Garreta, Elena; Marco, Andrés; Izpisúa Belmonte, Juan Carlos; Montserrat, Núria (Data de publicació: 2017-06-12)

Although mouse models have represented a major tool for understanding and predicting molecular mechanisms responsible for several human genetic diseases, still species-specific differences between mouse and humans in their ...

The generation of a lactate-rich environment stimulates cell cycle progression and modulates gene expression on neonatal and hiPSC-derived cardiomyocytes 

Ordoño, Jesús; Pérez Amodio, Soledad; Ball, Kristen; Aguirre, Aitor; Engel, Elisabeth (Data de publicació: 2022-09-16)

In situ tissue engineering strategies are a promising approach to activate the endogenous regenerative potential of the cardiac tissue helping the heart to heal itself after an injury. However, the current use of complex ...

Light-induced regulation of ligand-gated channel activity 

Bregestovski, Piotr; Maleeva, Galyna; Gorostiza Langa, Pablo Ignacio (Data de publicació: 2020-06-01)

The control of ligand-gated receptors with light using photochromic compounds has evolved from the first handcrafted examples to accurate, engineered receptors, whose development is supported by rational design, high-resolution ...

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