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IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Recent submissions

Now showing items 521-540 of 3164

    Undetected displacement of a subcutaneous implantable cardioverter-defibrillator lead 

    Apolo, José; San Antonio, Rodolfo; Mont Girbau, Lluís; Tolosana, José M. (José María) (Publication date: 2020-06-01)

    Background: In recent years, subcutaneous implantable cardioverter-defibrillator (S-ICD) implants have progressively increased and have been shown to be safe and highly successful, affording low reintervention rates ...

    Comparative analysis of calcineurin-inhibitor-based methotrexate and mycophenolate mofetil-containing regimens for prevention of Graft-versus-Host Disease after reduced intensity conditioning allogeneic transplantation 

    Chhabra, Saurabh; Liu, Ying; Hemmer, Michael T.; Costa, Luciano; Pidala, Joseph A.; Couriel, Daniel R.; Alousi, Amin M.; Majhail, Navneet S.; Stuart, Robert K.; Kim, Dennis; Ringden, Olle; Urbano Ispizua, Álvaro; Saad, Ayman; Savani, Bipin N.; Cooper, Brenda; Marks, David I.; Socie, Gerard; Schouten, Harry C.; Schoemans, Helen; Abdel Azim, Hisham; Yared, Jean; Cahn, Jean-Yves; Wagner, John; Antin, Joseph H.; Verdonck, Leo F.; Lehmann, Leslie; Aljurf, Mahmoud; MacMillan, Margaret L.; Litzow, Mark R.; Solh, Melhem M.; Qayed, Muna; Hematti, Peiman; Kamble, Rammurti T.; Vij, Ravi; Hayashi, Robert J.; Gale, Robert Peter; Martino, Rodrigo; Seo, Sachiko; Hashmi, Shahrukh K.; Nishihori, Taiga; Teshima, Takanori; Gergis, Usama; Inamoto, Yoshihiro; Spellman, Stephen R.; Arora, Mukta; Hamilton, Betty K (Publication date: 2021-06-15)

    The combination of a calcineurin inhibitor (CNI) such as tacrolimus (TAC) or cyclosporine (CYSP) with methotrexate (MTX) or with mycophenolate mofetil (MMF) has been commonly used for graft-versus-host disease (GVHD) ...

    2016 Expert consensus document on prevention, diagnosis and treatment of short-term peripheral venous catheter-related infections in adult. 

    Capdevila, Josep A.; Guembe, María; Barberán, José; Alarcón, Aristides de; Bouza, Emilio; Fariñas, María Carmen; Gálvez, Juan; Goenaga Sánchez, Miguel Ángel; Gutiérrez, Francisco; Kestler, Martha; Llinares, Pedro; Miró Meda, José M. (José María), 1956-; Montejo, Miguel; Muñoz, Patricia; Rodríguez Creixems, Marta; Sousa, Dolores; Cuenca, José; Mestres Lucio, Carlos-Alberto (Publication date: 2017-04-05)

    Aquest document també està publicat a: 'Cirugía Cardiovascular' http://dx.doi.org/10.1016/j.circv.2016.06.001

    Antioxidant Molecular Brain Changes Parallel Adaptive Cardiovascular Response to Forced Running in Mice 

    Bartra, Clara; Jager, Lars Andre; Alcarraz, Anna; Meza Ramos, Aline; Sangüesa Puigventós, Gemma; Corpas Expósito, Rubén; Guasch i Casany, Eduard; Batlle, Montserrat; Sanfeliu i Pujol, Coral (Publication date: 2023-08-01)

    Physically active lifestyle has huge implications for the health and well-being of people of all ages. However, excessive training can lead to severe cardiovascular events such as heart fibrosis and arrhythmia. In addition, ...

    Aphasia in a patient with acute hepatic encephalopathy associated with multifocal cortical brain lesions (Letter) 

    Falgàs Martínez, Neus; Alfaro, I.; Crespo Conde, Gonzalo; Berenguer, J.; García Pagán, Juan Carlos; Muñoz Garcia, Jose Esteban (Publication date: 2022-07-01)

    La encefalopatía hepática aguda (EHA) se caracteriza típicamente por una amplia gama de manifestaciones neuropsiquiátricas incluyendo alteraciones del comportamiento, estado de ánimo o cognitivas asociadas a asterixis y ...

    Recomendaciones de disponibilidad y utilizacion de antídotos en los hospitales según su nivel de complejidad asistencia 

    Aguilar Salmerón, Raquel; Martínez Sánchez, Lidia; Broto Sumalla, Antoni; Fernández de Gamarra Martínez, Edurne; García Pelaéz, Milagros; Nogué Xarau, Santiago (Publication date: 2017-03-30)

    The stocking of antidotes in various care settings is a subject of debate. A group of experts in hospital pharmacy and both adult and pediatric clinical toxicology was formed to review the Spanish and international literature ...

    Serum Phospholipids Fatty Acids and Breast Cancer Risk by Pathological Subtype 

    Lope, Virginia; Guerrero Zotano, Ángel; Casas, Ana; Baena Cañada, José Manuel; Bermejo, Begona; Pérez Gómez, Beatriz; Criado Navarro, Inmaculada; Antolín, Silvia; Sánchez Rovira, Pedro; Ramos Vázquez, Manuel; Antón, Antonio; Castelló, Adela; García Saenz, Jose Angel; Muñoz Mateu, Montserrat; Juan, Ana de; Andrés, Raquel; Llombart Cussac, Antonio; Hernando, Blanca; Franquesa, Rosa María; Caballero, Rosalía; Priego Capote, Feliciano; Martón, Miguel; Pollán, Marina (Publication date: 2021-04-15)

    This study evaluates whether serum phospholipids fatty acids (PL-FAs) and markers of their endogenous metabolism are associated with breast cancer (BC) subtypes. EpiGEICAM is a Spanish multicenter matched case-control ...

    Differentially Deregulated MicroRNAs as Novel Biomarkers for Neoplastic Progression in Ulcerative Colitis 

    Quintanilla Leo, Isabel; Jung, Gerhard; Jimeno, Mireya; Lozano Salvatella, Juan José; Sidorova, Julia; Camps, Jordi; Carballal, Sabela; Bujanda, Luis; Vera, María Isabel; Quintero, Enrique; Carrillo Palau, Marta; Cuatrecasas Freixas, Miriam; Castells Garangou, Antoni; Panés Díaz, Julià; Ricart, Elena; Moreira Ruiz, Leticia; Balaguer Prunés, Francesc; Pellisé Urquiza, Maria (Publication date: 2024-03-27)

    Introduction: Colorectal cancer (CRC) is a potentially life-threatening complication of long-standing ulcerative colitis (UC). MicroRNAs (miRNA) are epigenetic regulators that have been involved in the development of ...

    Deconstructing major depressive episodes across unipolar and bipolar depression by severity and duration: a cross-diagnostic cluster analysis on a large, international, observational study 

    Corponi, Filippo; Anmella, Gerard; Pacchiarotti, Isabella; Samalin, Ludovic; Verdolini, Norma; Popovic, Dina; Azorin, Jean-Michel; Angst, Jules; Bowden, Charles L.; Mosolov, Sergey; Young, Allan H.; Perugi, Giulio; Vieta i Pascual, Eduard, 1963-; Murru, Andrea (Publication date: 2021-03-22)

    A cross-diagnostic, post-hoc analysis of the BRIDGE-II-MIX study was performed to investigate how unipolar and bipolar patients suffering from an acute major depressive episode (MDE) cluster according to severity and ...

    Aggressiveness in depression: a neglected symptom possibly associated with bipolarity and mixed features 

    Verdolini, Norma; Perugi, Giulio; Samalin, Ludovic; Murru, Andrea; Angst, Jules; Azorin, Jean-Michel; Bowden, Charles L.; Mosolov, Sergey; Young, Allan H.; Barbuti, Margherita; Guiso, Giovanni; Popovic, Dina; Vieta i Pascual, Eduard, 1963-; Pacchiarotti, Isabella; BRIDGE-II-Mix Study Group (Publication date: 2020-01-20)

    OBJECTIVE: To evaluate aggressiveness during a major depressive episode (MDE) and its relationship with bipolar disorder (BD) in a post hoc analysis of the BRIDGE-II-MIX study. METHOD: A total of 2811 individuals were ...

    Impact of the new definition for pulmonary hypertension in patients with lung disease: an analysis of the United Network for Organ Sharing database 

    Nathan, Steven D.; Barnett, Scott D.; King, Christopher S.; Provencher, Steeve; Barberà i Mir, Joan Albert; Pastre, Jean; Shlobin, Oksana A.; Seeger, Werner (Publication date: 2022-03-01)

    The implications of the recent change in the definition of pulmonary hypertension on epidemiology and outcomes are not known. We sought to determine the percentage of patients with the two most common lung diseases that ...

    Brain network interactions in transgender individuals with gender incongruence 

    Uribe, Carme; Junqué i Plaja, Carme, 1955-; Gómez Gil, Esther; Abós, Alexandra; Mueller, Sven C.; Guillamon, Antonio (Publication date: 2022-03-09)

    Functional brain organization in transgender persons remains unclear. Our aims were to investigate global and regional connectivity differences within functional networks in transwomen and transmen with early-in-life onset ...

    Predictors of severe sepsis among patients hospitalized for community-acquired pneumonia 

    Montull, Beatriz; Menéndez, Rosario; Torres Martí, Antoni; Reyes, Soledad; Méndez, Raúl; Zalacaín, Rafael; Capelastegui, Alberto; Rajas, Olga; Borderías, Luis; Martín Villasclaras, Juan; Bello, Salvador; Alfageme, Inmaculada; Rodríguez de Castro, Felipe; Rello Condomines, Jordi; Molinos, Luis; Ruiz Manzano, Juan (Publication date: 2017-01-02)

    Background Severe sepsis, may be present on hospital arrival in approximately one-third of patients with community-acquired pneumonia (CAP). Objective To determine the host characteristics and micro-organisms associated ...

    The complex association between the antioxidant defense system and clinical status in early psychosis 

    García, Saínza; Alberich, Susana; Martínez Cengotitabengoa, Mónica; Arango, Celso; Castro Fornieles, Josefina; Parellada, Mara; Baeza, Inmaculada, 1970-; Moreno, Carmen (Moreno Koch); Micó, Juan Antonio; Berrocoso, Esther; Graell, Montserrat; Otero, Soraya; Simal, Tatiana; González-Pinto, Ana (Publication date: 2020-01-22)

    Oxidative stress is a pathophysiological mechanism potentially involved in psychiatric disorders. The objective of this study was to assess the relationship between total antioxidant status (TAS) and the functional status ...

    Effects of JNJ-46356479 and clozapine on VGLUT1 and GAD65/67 brain levels and expression of genes related to glutamate and GABA in mice postnatally exposed to ketamine. 

    Martínez Pinteño, Albert; Olivares Berjaga, David; Rodríguez Ferret, Natalia; Mena, Juan Ignacio; Prohens Coll, Llucia; Mas Herrero, Sergi; Morén Núñez, Constanza; Parellada Rodón, Eduard; Gassó Astorga, Patricia (Publication date: 2026-02-27)

    Schizophrenia (SZ) is a complex mental disorder influenced by genetic, environmental, and neurobiological factors, with current treatments ineffective for negative symptoms and cognitive deficits. The glutamatergic hypothesis ...

    Toward precision psychiatry in bipolar disorder: staging 2.0 

    Salagre Muñoz, Estela; Dodd, Seetal; Aedo, Alberto; Rosa, Adriane Ribeiro; Amoretti Guadall, Silvia; Pinzon Espinosa, Justo Emilio; Reinares, María; Berk, Michael; Kapczinski, Flávio; Vieta i Pascual, Eduard, 1963-; Grande i Fullana, Iria (Publication date: 2019-12-02)

    Personalized treatment is defined as choosing the "right treatment for the right person at the right time." Although psychiatry has not yet reached this level of precision, we are on the way thanks to recent technological ...

    Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants. 

    Vidal Marsal, Francisco; López Dupla, Miguel; Laguno Centeno, Montserrat; Veloso, Sergi; Mallolas Masferrer, Josep; Murillas Angoiti, Javier; Cifuentes, Carmen; Gallart, Lluis; Auguet, Teresa; Sampériz, Gloria; Payeras, Antoni; Hernandez, Pilar; Arnedo, Mireia; Gatell, José M.; Richart, Cristóbal (Publication date: 2018-09-25)

    Background and Aims This was a safety and efficacy pharmacogenetic study of a previously performed randomized trial which compared the effectiveness of treatment of hepatitis C virus infection with pegylated interferon ...

    Adipocyte fatty-acid binding protein is overexpressed in cirrhosis and correlates with clinical outcomes 

    Graupera, Isabel; Coll, Mar; Pose Méndez, Elisa; Elia, Chiara; Piano, Salvatore; Solà, Elsa; Blaya, Delia; Huelin, Patricia; Solé Padullés, Cristina; Moreira, Rebeca; de la Prada, Gloria; Fabrellas i Padrès, Núria; Juanola, Adrià; Morales Ruiz, Manuel; Sancho Bru, Pau; Villanueva Sánchez, Càndid; Ginès i Gibert, Pere (Publication date: 2018-02-28)

    Fatty-acid-binding proteins (FABPs) are small intracellular proteins that coordinate lipid-mediated processes by targeting metabolic and immune response pathways. The aim of the study was to investigate plasma FABPs levels ...

    Characterization of digestive involvement in patients with chronic T. cruzi infection in Barcelona, Spain 

    Pinazo, Maria-Jesus; Lacima Vidal, Gloria; Elizalde, J. Ignasi; Posada, Elizabeth; Gimeno, Fausto; Aldasoro, Edelweiss; Valls, M. Eugenia; Gascón i Brustenga, Joaquim (Publication date: 2020-01-14)

    Background: Digestive damage due to Chagas disease (CD) occurs in 15-20% of patients diagnosed as a result of peristaltic dysfunction in some endemic areas. The symptoms of chronic digestive CD are non-specific, and there ...

    Role of Circulating Angiotensin Converting Enzyme 2 in Left Ventricular Remodeling following Myocardial Infarction: A Prospective Controlled Study. 

    Ortiz Pérez, José Tomás; Riera, Marta; Bosch Genover, Xavier; Caralt Robira, Ma. Teresa de; Perea Palazón, Rosario Jesús; Pascual, Julio (Pascual Santos); Soler, María José (Publication date: 2018-07-24)

    Angiotensin-converting enzyme 2 (ACE2) cleaves Angiotensin-II to Angiotensin-(1-7), a cardioprotective peptide. Serum soluble ACE2 (sACE2) activity is raised in chronic heart failure, suggesting a compensatory role in left ...