Reference Gene Validation for RT-qPCR in PBMCs from Asthmatic Patients with or without Obesity 

Bantulà, Marina; Arismendi, Ebymar; Picado Vallés, César; Roca i Ferrer, Jordi; Mullol i Miret, Joaquim; Tubita, Valeria (Publication date: 2023-06-21)

Obesity is known to impair the efficacy of glucocorticoid medications for asthma control. Glucocorticoid-induced gene expression studies may be useful to discriminate those obese asthmatic patients who present a poor ...

Advances in Using MRI to Estimate the Risk of Future Outcomes in Mental Health - Are We Getting There? 

Solanes, Aleix; Radua, Joaquim (Publication date: 2024-01-24)

Schizophrenia is a mental disorder among the leading disabling conditions worldwide. It affects approximately 20 million people and increases 2–3 times the probability of dying early and decreases the life expectancy by ...

Gender differences in GPs' strategies for coping with the stress of the COVID-19 pandemic in Catalonia: A cross-sectional study 

Aragonès, E.; Fernández San-Martín, M.; Rodríguez Barragán, M.; Martín Luján, F.; Solanes, M.; Berenguera, A.; Sisó Almirall, Antoni; Basora, J. (Publication date: 2024-03-25)

The Covid-19 pandemic has increased stress levels in GPs, who have resorted to different coping strategies to deal with this crisis. Gender differences in coping styles may be contributing factors in the development of ...

Diagnostic Performance and Clinical Applicability of Blood-Based Biomarkers in a Prospective Memory Clinic Cohort 

Sarto Alonso, Jordi; Ruiz García, Raquel; Guillén Soley, Núria; Ramos Campoy, Oscar; Falgàs Martínez, Neus; Esteller Gauxax, Diana; Contador Muñana, Jose Miguel; Fernández Villullas, Guadalupe; Gonzalez Romero, Yolanda; Tort Merino, Adrià; Juncà Parella, Jordi; Bosch Capdevila, Beatriz; Borrego Écija, Sergi; Molina Porcel, Laura; Castellví Sampol, Magdalena; Vergara Orgilles, Miguel; Antonell Boixader, Anna, 1978-; Augé Fradera, Josep Maria; Naranjo, L.; Sanchez del Valle Díaz, Raquel; Lladó Plarrumaní, Albert; Balasa, Mircea (Publication date: 2024-08-30)

Blood-based biomarkers have emerged as minimally-invasive options for evaluating cognitive impairment. Most studies to date have assessed them in research cohorts, limiting their generalization to everyday clinical practice. ...

An artificial intelligence-assisted system versus white light endoscopy alone for adenoma detection in individuals with Lynch syndrome (TIMELY): an international, multicentre, randomised controlled trial 

Ortiz Zúñiga, Oswaldo; Daca Alvarez, Maria de los Angeles; Rivero Sanchez, Liseth; Gimeno Garcia, Antonio Z.; Carrillo Palau, Marta; Alvarez, Victoria; Ledo Rodriguez, Alejandro; Ricciardiello, Luigi; Pierantoni, Chiera; Hueneburg, Robert; Nattermann, Jacob; Bisschops, Raf; Tejpar, Sabine; Huerta, Alain; Pons, Faust Riu; Alvarez Urturi, Cristina; Lopez Vicente, Jorge; Repici, Alessandro; Hassan, Cessare; Cid, Lucia; Cavestro, Giulia Martina; Romero Mascarell, Cristina; Gordillo, Jordi; Puig, Ignasi; Herraiz, Maite; Betes, Maite; Herrero, Jesús; Jover, Rodrigo; Balaguer Prunés, Francesc; Pellisé Urquiza, Maria; TIMELY study group (Publication date: 2024-11-15)

Background Computer-aided detection (CADe) systems for colonoscopy have been shown to increase small polyp detection during colonoscopy in the general population. People with Lynch syndrome represent an ideal target ...

Perception and control of a virtual body in immersive virtual reality for rehabilitation 

Donegan, Anthony; Sánchez-Vives, María Victoria (Publication date: 2025-02-17)

Purpose of reviewThis review explores recent advances in using immersive virtual reality to improve bodily perception and motor control in rehabilitation across musculoskeletal and neurological conditions, examining how ...

Emerging issues on Staphylococcus aureus endocarditis and the role in therapy of daptomycin plus fosfomycin 

García de la Mària, Cristina; Cañas, María Alexandra; Fernández Pittol, Mariana; Dahl, Anders; García González, Javier; Hernández Meneses, Marta; Cuervo Requena, Guillermo; Moreno, Asunción; Miró Meda, José M. (José María), 1956-; Marco, Francesc (Publication date: 2024-01-24)

IntroductionMethicillin-resistant and -susceptible Staphylococcus aureus (MRSA/MSSA) infections are a major global health-care problem. Bacteremia with S. aureus exhibits high rates of morbidity and mortality and can cause ...

The emergency department arrival mode and its relations to ED management and 30-day mortality in acute heart failure: an ancillary analysis from the EURODEM study 

Harjola, P.; Tarvasmaki, T.; Barletta, C.; Body, R.; Capsec, J.; Christ, M.; Garcia Castrillo, L.; Golea, A.; Karamercan, M. A.; Martin, P. L.; Miró i Andreu, Òscar; Tolonen, J.; van Meer, O.; Palomaki, A.; Verschuren, F.; Harjola, V. P.; Laribi, S. (Publication date: 2024-03-25)

Background Acute heart failure patients are often encountered in emergency departments (ED) from 11% to 57% using emergency medical services (EMS). Our aim was to evaluate the association of EMS use with acute heart failure ...

Call for Action: Benzodiazepine Prescription Prevalence Analysis Shows Off-Label Prescription in One in Eleven Citizens 

López Pelayo, Hugo; Coma, Anna; Gual, Antoni; Zara, Corinne; Lligoña, Anna (Publication date: 2020-03-01)

Objective: Benzodiazepines have a good safety profile. Nevertheless, off-label use of these drugs may increase the risk of falls, dependence, and memory loss. Off-label prescription use is not highly prevalent. Studies ...

Implementation of a New Protocol for Direct Identification from Urine in the Routine Microbiological Diagnosis 

Zboromyrska, Yuliya; Rico, Verónica; Pitart, Cristina; Fernandez Pittol, Mariana José; Soriano,Àlex; Bosch Mestres, Jordi (Publication date: 2023-05-12)

The direct identification of uropathogens from urine samples, in combination with the rapid detection of resistance, would allow early adjustment of empirical antimicrobial treatment.Two hundred and ninety-eight urine ...

Decreased practice effects in cognitively unimpaired amyloid betapositive individuals: a multicenter, longitudinal, cohort study 

Tort Merino, Adrià; Pérez Millan, Agnès; Falgàs Martínez, Neus; Borrego Écija, Sergi; Esteller, Diana; Bosch, Bea; Castellví, Magdalena; Juncà Parella, Jordi; Val Guardiola, Andrea; Fernández Villullas, Guadalupe; Antonell Boixader, Anna, 1978-; Sanchez-Saudinos, María Belén; Rubio Guerra, Sara; Zhu, Nuole; García Martínez, María; Pozueta, Ana; Estanga, Ainara; Ecay Torres, Mirian; Lopez de Luis, Carolina; Tainta, Mikel; Altuna, Miren; Rodriguez Rodriguez, Eloy; Sanchez Juan, Pascual; Martinez Lage, Pablo; Lleo, Alberto; Fortea, Juan; Illán Gala, Ignacio; Balasa, Mircea; Lladó Plarrumaní, Albert; Rami González, Lorena; Sánchez Valle, Raquel (Publication date: 2025-10-30)

INTRODUCTION We aimed to determine whether cognitively unimpaired (CU) amyloid- beta-positive (A beta+) individuals display decreased practice effects on serial neuropsychological testing. METHODS We included 209 CU ...

High-Intensity Exercise Promotes Deleterious Cardiovascular Remodeling in a High-Cardiovascular-Risk Model: A Role for Oxidative Stress 

Meza Ramos, Aline; Alcarraz, Anna; Lazo Rodríguez, Marta; Sangüesa Puigventós, Gemma; Bañón Maneus, Elisenda; Rovira Juárez, Jordi; Ramírez Bajo, María José; Sitges, Marta; Mont Girbau, Lluís; Ventura Aguiar, Pedro; Batlle, Montserrat; Guasch i Casany, Eduard (Publication date: 2024-01-24)

Respiratory infections 

Niederman, Michael S.; Torres Martí, Antoni (Publication date: 2024-01-30)

Respiratory infections, whether acute or chronic, are extremely frequent in both adults and children, representing an increased economic burden on healthcare systems, morbidity and mortality. These infections can be either ...

Early Brain Volume Changes After Stroke: Subgroup Analysis From the AXIS-2 Trial 

Bu, Ning; Churilov, Leonid; Khlif, Mohamed Salah; Lemmens, Robin; Wouters, Anke; Fiebach, Jochen B.; Chamorro Sánchez, Ángel; Ringelstein, E. Bernd; Norrving, Bo; Laage, Rico; Grond, Martin; Wilms, Guido; Brodtmann, Amy; Thijs, Vincent (Publication date: 2023-06-19)

Background and PurposeThe evolution of total brain volume early after stroke is not well understood. We investigated the associations between age and imaging features and brain volume change in the first month after stroke. ...

Viral community-acquired pneumonia: what’s new since COVID-19 emerged? 

Cillóniz, Catia; Videla, Alejandro J.; Pulido, Laura; Uy King, Mary Joy (Publication date: 2025-04-28)

Introduction All over the world, viral pneumonia has a significant impact on morbidity and mortality, especially among vulnerable populations. The most common respiratory viruses causing pneumonia include influenza virus, ...

Proposed Definitions of Antibody-Mediated Rejection for Use as a Clinical Trial Endpoint in Kidney Transplantation 

Roufosse, Candice; Becker, Jan Ulrich; Rabant, Marion; Seron, Daniel; Bellini, Maria Irene; Böhmig, Georg A.; Budde, Klemens; Diekmann, Fritz; Glotz, Denis; Hilbrands, Luuk; Loupy, Alexandre; Oberbauer, Rainer; Pengel, Liset; Schneeberger, Stefan; Naesens, Maarten (Publication date: 2024-01-24)

Antibody-mediated rejection (AMR) is caused by antibodies that recognize donor human leukocyte antigen (HLA) or other targets. As knowledge of AMR pathophysiology has increased, a combination of factors is necessary to ...

Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis 

Baldwin, Helen; Radua, Joaquim; Antoniades, Mathilde; Haas, Shalaila S.; Frangou, Sophia; Agartz, Ingrid; Allen, Paul; Andreassen, Ole A.; Atkinson, Kimberley; Bachman, Peter; Baeza, Inmaculada; Bartholomeusz, Cali F.; Chee, Michael W. L.; Colibazzi, Tiziano; Cooper, Rebecca E.; Corcoran, Cheryl M.; Cropley, Vanessa L.; Ebdrup, Bjørn H.; Fortea, Adriana; Glenthøj, Louise Birkedal; Hamilton, Holly K.; Haut, Kristen M.; Hayes, Rebecca A.; He, Ying; Heekeren, Karsteen; Kaess, Michael; Kasai, Kiyoto; Katagiri, Naoyuki; Kim, Minah; Kindler, Jochen; Klaunig, Mallory J.; Koike, Shinsuke; Koppel, Alex; Kristensen, Tina D.; Bin Kwak, Yoo; Kwon, Jun Soo; Lawrie, Stephen M.; Lebedeva, Irina; Lee, Jimmy; Lin, Ashleigh; Sugranyes, Gisela; Fusar Poli, Paolo; ENIGMA Clinical High Risk for Psychosis Working Group (Publication date: 2024-01-24)

Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical heterogeneity in the CHR-P state is largely undetermined. ...

Effect of lipopolysaccharide on glucocorticoid receptor function in control nasal mucosa fibroblasts and in fibroblasts from patients with chronic rhinosinusitis with nasal polyps and asthma 

Fernández Bertolín, Laura; Mullol i Miret, Joaquim; Fuentes Prado, Mireya; Roca i Ferrer, Jordi; Alobid, Isam; Picado Vallés, César; Pujols Tarrés, Laura (Publication date: 2020-06-17)

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease of the upper airways frequently associated with asthma. Bacterial infection is a feature of CRSwNP that can aggravate the disease and the ...

Transcriptional Profile Associated with Clinical Outcomes in Metastatic Hormone-Sensitive Prostate Cancer Treated with Androgen Deprivation and Docetaxel 

Jimenez, Natalia; Reig Torras, Oscar; Marin Aguilera, Mercedes; Aversa, Caterina; Ferrer Mileo, Laura; Font, Albert; Rodriguez Vida, Alejo; Climent, Miguel Ángel; Cros, Sara; Chirivella, Isabel; Domenech, Montserrat; Figols, Mariona; González Billalabeitia, Enrique; Jiménez Peralta, Daniel; Rodriguez Carunchio, Leonardo; Garcia Esteve, Samuel; García de Herrero, Marta; Ribal, María José; Prat Aparicio, Aleix; Mellado González, Begoña (Publication date: 2023-04-27)

Background: Androgen deprivation therapy (ADT) and docetaxel (DX) combination is a standard therapy for metastatic hormone-sensitive prostate cancer (mHSPC) patients. (2) Methods: We investigate if tumor transcriptomic ...

El corazón de las personas que nacieron con bajo peso podría ser distinto del de los demás 

Crispi Brillas, Fàtima; Sepúlveda-Martínez, Álvaro; Rodríguez-Lopez, Merida (Publication date: 2022-11-09)

Si durante el embarazo el feto experimenta una falta de nutrientes, intentará ahorrar y engordará menos. Sin embargo, esto puede tener importantes consecuencias en su salud adulta.