Alzheimer's disease phenotypes show different sleep architecture 

Falgàs Martínez, Neus; Walsh, Christine M.; Yack, Leslie; Simon, Alexander J.; Allen, Isabel E.; Kramer, Joel H.; Rosen, Howard J.; Joie, Renaud La; Rabinovici, Gil D.; Miller, Bruce; Spina, Salvatore; Seeley, William W.; Ranasinghe, Kamalini; Vossel, Keith; Neylan, Thomas C.; Grinberg, Lea T. (Data de publicació: 2024-04-24)

Sleep-wake disturbances are a prominent feature of Alzheimer's disease (AD). Atypical (non-amnestic) AD syndromes have different patterns of cortical vulnerability to AD. We hypothesized that atypical AD also shows ...

Long-term survival after cardiac arrest in patients undergoing emergent coronary angiography 

Vidal Calés, Pablo; Ortega Paz, Luis; Brugaletta, Salvatore; García Penayo, John; Rodes Cabau, Josep; Angiolillo, Dominick J; Regueiro Cueva, Ander; Freixa Rofastes, Xavier; Abdul Jawad Altisent, Omar; Cepas Guillen, Pedro Luis; Andrea Riba, Rut; Diego Soler, Oriol de; Tizón Marcos, Helena; Tomás Querol, Carlos; Gómez Hospital, Joan Antoni; Carrillo, Xavier; Cárdenas, Merida; Rojas, Sergio; Munoz Camacho, Juan Francisco; Garcia Picart, Joan; Lidon, Rosa Maria; Sabaté Tenas, Manuel (Data de publicació: 2025-01-08)

Aim: To determine long-term survival of patients after cardiac arrest undergoing emergent coronary angiography and therapeutic hypothermia. Methods: We analysed data from patients treated within the regional STEMI Network ...

Sperm proteomic changes associated with early embryo quality after ICSI 

Jodar Bifet, Meritxell; Attardo Parrinello, Claudio; Soler Ventura, Ada; Barrachina Villalonga, Ferran; Delgado Dueñas, David; Civico, Salvadora; Calafell, Josep Maria; Ballescà, Josep Lluís; Oliva Virgili, Rafael (Data de publicació: 2024-06-06)

Research question: Do alterations of human sperm protein profile affect embryo quality? Design: Sperm proteins from 27 infertile couples undergoing intracytoplasmic sperm injection (ICSI) were extracted and digested. The ...

Hemodynamic profile of terlipressin and octreotide in patients with cirrhosis and portal hypertension: A randomized, single-blind clinical trial 

Perez Campuzano, Valeria; Olivas, Pol; Ferrusquia Acosta, José; Torres, Sonia; Borras, Roger; Baiges Aznar, Anna; Orts, Lara; Vizcarra, Pamela; Falga, María Ángeles; Codina, Joana; Shalaby, Sarah; Ojeda Gómez, Asunción; Turon, Fanny; Hernández Gea, Virginia; Cárdenas Vásquez, Andrés; García Pagán, Juan Carlos (Data de publicació: 2025-03-03)

Background and aims Continuous infusion (CI) of terlipressin may result in a more sustained reduction in portal pressure with fewer adverse effects than administered as a bolus. This study aimed to compare the hepatic and ...

Current outcomes of SARS-CoV-2 Omicron variant infection in high-risk haematological patients treated early with antivirals 

Aiello, Tommaso Francesco; Puerta-Alcalde, Pedro; Chumbita, Mariana; Lopera, Carlos; Monzó Gallo, Patricia; Cortes, Albert; Fernández Avilés, Francesc; Suárez-Lledó Grande, María; Correa, Juan; Ortiz-Maldonado Gibson, Valentín; Cuesta, Genoveva; Martínez Cibrian, Nuria; Esteve Reyner, Jordi; Marcos, María Ángeles; Mensa, Josep; Soriano Viladomiu, Alex; Garcia Vidal, Carolina (Data de publicació: 2024-01-24)

Altered expression of the immunoregulatory ligand-receptor pair CD200-CD200R1 in the brain of Parkinson's disease patients 

Rabaneda Lombarte, Neus; Vidal Taboada, José Manuel; Valente, Tony; Ezquerra Trabalón, Mario; Fernández Santiago, Rubén; Martí Domènech, Ma. Josep; Compta, Yaroslau; Saura Martí, Josep; Solà i Subirana, Carme (Data de publicació: 2024-01-24)

Neuroinflammation, in which activated microglia are involved, appears to contribute to the development of Parkinson's disease (PD). However, the role of microglial activation and the mechanisms governing this process remain ...

Epidemiology of Melanoma in Spain: Estimation of Number of Patients With Stage III Disease Eligible for Adjuvant Therapies 

Puig i Sardà, Susana; Martínez Fernández, A.; Nagore, Eduardo; Moreno Ramírez, David; Ortiz Romero, Pablo Luis; Martín Sánchez , Eva (Data de publicació: 2023-07-24)

Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes 

Graus, Francesc; Vogrig, Alberto; Muñiz Castrillo, Sergio; Prüss, Harald; Desestret, Virginie; Dubey, Divyanshu; Giometto, Bruno; Irani, Sarosh R.; Leypoldt, Frank; McKeon, Andrew; Honnorat, Jerome; Psimaras, Dimitri; Thomas, Laure; Antoine, Jean-Christophe G.; Titulaer, Maarten J.; Vedeler, Christian A.; Verschuuren, Jan J.; Dalmau Obrador, Josep; Joubert, Bastien (Data de publicació: 2022-03-09)

The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs) requires an increasing understanding of their clinical, immunologic, and oncologic heterogeneity. The 2004 PNS criteria are partially outdated due ...

Examining the variability of neurocognitive functioning in individuals at clinical high risk for psychosis: a meta-analysis 

Catalán, Ana; Radua, Joaquim; McCutcheon, Robert; Aymerich, Claudia; Pedruzo, Borja; González Torres, Miguel Ángel; Baldwin, Helen; Stone, William S.; Giuliano, Anthony J.; Mcguire, Philip; Fusar-Poli, Paolo (Data de publicació: 2023-07-21)

This study aims to meta-analytically characterize the presence and magnitude of within-group variability across neurocognitive functioning in young people at Clinical High-Risk for psychosis (CHR-P) and comparison groups. ...

An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents 

Moeini, Agrin; Torrecilla, Sara; Tovar, Victoria; Montironi, Carla; Andreu Oller, Carmen; Peix, Judit; Higuera, Mónica; Pfister, Dominik; Ramadori, Pierluigi; Pinyol, Roser; Solé, Manel; Heikenwälder, Mathias; Friedman, Scott L.; Sia, Daniela; Llovet i Bayer, Josep Maria (Data de publicació: 2020-01-08)

Cirrhosis and chronic inflammation precede development of hepatocellular carcinoma (HCC) in approximately 80% of cases. We investigated immune-related gene expression patterns in liver tissues surrounding early-stage HCCs ...

Pertussis vaccination during pregnancy: Antibody persistence in infants 

Vilajeliu, Alba; Ferrer, Laia; Munrós Feliu, Jordina; Goncé Mellgren, Anna; López, Marta; Costa, Josep; Bayas Rodríguez, José María (Data de publicació: 2016-09-08)

Maternal pertussis vaccination is associated with higher levels of pertussis antibodies at birth. We assessed the persistence of pertussis antibodies until primary vaccination in infants ...

Functional Evidence of <i>CCDC186</i> as a New Disease-Associated Gene with Endocrine and Central Nervous System Alterations 

Arrabal, L.; Muñoz Pujol, G.; Medina Martínez, I.; Gort, L.; García Villoria, Judit; Roldán, S.; Tort, Frederic; Ribes Rubió, Maria Antònia (Data de publicació: 2024-02-19)

Unilateral axilo-breast approach (UABA) with gas insufflation versus open conventional hemithyroidectomy: A prospective comparative study 

Saavedra Pérez, David; Manyalich, Martí; Domínguez, Paula; Farguell, Jordi; Rull, Ramon; López Boado, Miguel A.; Vilaça, Jaime; Vidal Pérez, Oscar (Data de publicació: 2024-02-26)

Background: The objective of this study was to compare with the conventional open approach, the surgical and aesthetic results of endoscopic thyroidectomy via unilateral axillo-breast approach (UABA) with gas insufflation ...

Diagnostic yield of exome sequencing in fetal growth restriction: Systematic review and meta-analysis 

Pauta, Montse; Martínez Portilla, Raigam J.; Meler Barrabés, Eva; Otaño, Juan; Borrell, Antoni (Data de publicació: 2024-02-13)

To determine the diagnostic yield of exome sequencing (ES) above that of chromosomal microarray analysis (CMA) or karyotyping in fetuses with isolated fetal growth restriction (FGR) METHOD: This was a systematic review ...

Do Cultures Obtained During Primary THA Predict the Likelihood of Revision? 

Vargas Reverón, Caribay; Font Vizcarra, Lluís; Morata, Laura; Fernández Valencia, Jenaro A.; Soriano Viladomiu, Alex; Muñoz Mahamud, Ernesto (Data de publicació: 2024-01-24)

BackgroundThere can be unexpectedly positive culture results during elective hip arthroplasty, but the degree to which these are associated with an increased risk of subsequent premature revision is not known.Question/purposeAre ...

Cell death in hepatocellular carcinoma: Pathogenesis and therapeutic opportunities 

Garcia Pras, E.; Fernández Iglesias, A.; Gracia Sancho, J.; Pérez del Pulgar Gallart, Sofía (Data de publicació: 2024-02-07)

Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and the third leading cause of cancer death worldwide. Closely associated with liver inflammation and fibrosis, hepatocyte cell death is a common ...

Exercise Capacity in Children and Adolescents With Congenital Heart Disease: A Systematic Review and Meta-Analysis 

Villaseca Rojas, Yenny; Varela Melo, Javiera; Torres Castro, Rodrigo; Mazzucco, Guillermo; Vilaró, Jordi; Blanco Vich, Isabel; Vasconcello Castillo, Luis (Data de publicació: 2023-07-26)

Congenital heart disease (CHD) entails structural defects in the morphogenesis of the heart or its main vessels. Analyzing exercise capacity of children and adolescents with CHD is important to improve their functional ...

Optimal opportunistic screening of atrial fibrillation using pulse palpation in cardiology outpatient clinics: Who and how 

Bañeras, Jordi; Pariggiano, Ivana; Rodenas Alesina, Eduard; Oristrell, Gerard; Escalona, Roxana; Miranda, Berta; Rello, Pau; Soriano, Toni; Gordon, Blanca; Belahnech, Yassin; Calabró, Paolo; García Dorado, David; Ferreira González, Ignacio; Radua, Joaquim (Data de publicació: 2023-07-21)

Atrial fibrillation (AF) remain a prevalent undiagnosed condition frequently encountered in primary care.We aimed to find the parameters that optimize the diagnostic accuracy of pulse palpation to detect AF. We also aimed ...

Reference Gene Validation for RT-qPCR in PBMCs from Asthmatic Patients with or without Obesity 

Bantulà, Marina; Arismendi, Ebymar; Picado Vallés, César; Roca i Ferrer, Jordi; Mullol i Miret, Joaquim; Tubita, Valeria (Data de publicació: 2023-06-21)

Obesity is known to impair the efficacy of glucocorticoid medications for asthma control. Glucocorticoid-induced gene expression studies may be useful to discriminate those obese asthmatic patients who present a poor ...

Advances in Using MRI to Estimate the Risk of Future Outcomes in Mental Health - Are We Getting There? 

Solanes, Aleix; Radua, Joaquim (Data de publicació: 2024-01-24)

Schizophrenia is a mental disorder among the leading disabling conditions worldwide. It affects approximately 20 million people and increases 2–3 times the probability of dying early and decreases the life expectancy by ...