1. Inicio
  2. Universitat de Barcelona
  3. Fonaments Clínics
  4. Envíos recientes

Fonaments Clínics: Envíos recientes

Mostrando ítems 221-240 de 627

    Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells 

    López-Guerra, Mónica; Xargay i Torrent, Sílvia; Fuentes, Patricia; Roldán, Jocabed; González Farré, Blanca; Rosich, Laia; Silkenstedt, Elisabeth; García León, María J.; Lee-Vergés, Eriong; Giménez Carabaza, Neus; Giró, Ariadna; Aymerich Gregorio, Marta; Villamor i Casas, Neus; Delgado, Julio (Delgado González); López Guillermo, Armando; Puente, Xose S.; Campo Güerri, Elias; Toribio, María L.; Colomer Pujol, Dolors (Fecha de publicación: 2020-11-20)

    Targeting Notch signaling has emerged as a promising therapeutic strategy for chronic lymphocytic leukemia (CLL), particularly in NOTCH1-mutated patients. We provide first evidence that the Notch ligand DLL4 is a potent ...

    A dual role for KRT81: a miR-SNP associated with recurrence in non-small-cell lung cancer and a novel marker of squamous cell lung carcinoma 

    Campayo Guillaumes, Marc; Navarro Ponz, Alfons; Viñolas Segarra, Núria; Tejero Villalba, Rut; Muñoz García, Carmen; Díaz Sánchez, Tania; Marrades Sicart, Ramon Ma.; Cabanas, Maria L.; Gimferrer Garolera, José Ma.; Gascón, Pere; Ramírez Ruz, J. (José); Monzó Planella, Mariano (Fecha de publicación: 2013-06-26)

    MicroRNAs (miRNAs) play an important role in carcinogenesis through the regulation of their target genes. miRNA-related single nucleotide polymorphisms (miR-SNPs) can affect miRNA biogenesis and target sites and can alter ...

    Syndrome and outcome of antibody-negative limbic encephalitis 

    Graus Ribas, Francesc; Escudero, Domingo; Oleaga Zufiría, Laura; Bruna, Jordi; Villarejo Galende, Alberto; Ballabriga, Jordi; Barceló, María Inés; Gilo, Francisco; Popkirov, Stoyan; Stourac, Pavel; Dalmau Obrador, Josep (Fecha de publicación: 2020-11-30)

    Background and purpose: The aim was to report the clinical characteristics of 12 patients with limbic encephalitis (LE) who were antibody‐negative after a comprehensive immunological study. Methods: The clinical records ...

    Clinical role of subtraction ictal SPECT coregistered to MR Imaging and 18F-FDG PET in pediatric epilepsy 

    Perissinotti, Andrés; Setoain Perego, Xavier; Aparicio, Javier; Rubí Sureda, Sebastià; Marti Fuster, Berta; Donaire Pedraza, Antonio Jesús; Carreño, Mar; Bargalló Alabart, Núria; Rumià, Jordi; Garcia-Fructuoso, Gemma; Mayoral Peñalva, Maria; Sanmartí, Francesc; Pons Pons, Francisca (Fecha de publicación: 2015-09-01)

    A precise assessment of the drug-resistant epileptic pediatric population for surgical candidacy is often challenging, and to date there are no evidence-based guidelines for presurgical identification of the epileptogenic ...

    Burden and impact of Plasmodium vivax in pregnancy: A multi-centre prospective observational study 

    Bardají, Azucena; Martínez Espinosa, Flor E.; Arévalo-Herrera, Myriam; Padilla, Norma; Kochar, Swati; Ome-Kaius, Maria; Botto Menezes, Camila; Castellanos, Maria Eugenia; Kochar, Dhanpat K.; Kochar, Sanjay K.; Betuela, Inoni; Mueller, Ivo; Rogerson, Stephen John; Chitnis, Chetan E.; Hans, Dhiraj; Menegon, Michela; Severini, Carlo; Portillo Obando, Hernando A. del; Dobaño, Carlota, 1969-; Mayor Aparicio, Alfredo Gabriel; Ordi i Majà, Jaume; Piqueras, Mireia; Sanz, Sergi; Wahlgren, Mats; Slutsker, Laurence; Desai, Meghna; Menéndez, Clara; PregVax Study Group (Fecha de publicación: 2017-06-26)

    Podeu consultar dades primàries associades a l'article a: http://hdl.handle.net/2445/111582

    Molecular analysis of isoniazid and rifampin resistance in Mycobacterium tuberculosis isolates recovered from Barcelona. 

    Coll, Pere; Aragón, Lina Marcela; Alcaide Fernández de Vega, Fernando; Espasa, Mateo; Garrigó, Montserrat; González Martín, Julián; Manterola, Jose M.; Orús, Pilar; Salvadó, Margarita (Fecha de publicación: 2016-07-26)

    We studied the presence of mutations in the whole katG gene and specific regions of the oxyR-ahpC and mabA-inhA regulatory region in 61 Mycobacterium tuberculosis isoniazid-resistant isolates. An 81-bp region of the rpoB ...

    Emotional impact and compassion fatigue in oncology nurses: results of a multicentre study 

    Arimon-Pagès, Esther; Torres Puig-Gros, Joan; Fernández Ortega, Paz; Canela i Soler, Jaume (Fecha de publicación: 2019-12-12)

    Purpose: to assess the prevalence of Compassion Satisfaction, Compassion Fatigue (Burnout and Secondary Traumatic Stress) and anxiety in oncology nurses and the association with demographics, training, work-related conditions, ...

    Precisely tracking childhood death 

    Farag, Tamer H.; Koplan, Jeffrey P.; Breiman, Robert F.; Madhi, Shabir A.; Heaton, Penny M.; Mundel, Trevor; Ordi i Majà, Jaume; Bassat Orellana, Quique; Menéndez, Clara; Dowell, Scott F. (Fecha de publicación: 2017-07-27)

    Little is known about the specific causes of neonatal and under-five childhood death in high-mortality geographic regions due to a lack of primary data and dependence on inaccurate ...

    Emergence of progressive mutations in SARS-CoV-2 from a hematologic patient with prolonged viral replication 

    Garcia Vidal, Carolina; Iglesias, María; Puerta-Alcalde, Pedro; Mas, Vicente; Cuesta Chasco, Genoveva; García Pouton, Nicole; Varona, Sarai; Pozo, Francisco; Vázquez Morón, Sonia; Marcos, Ma. Angeles; Soriano Viladomiu, Alex; Casas Flecha, Inmaculada; HEMATOCOVID19-Researchers Group (Fecha de publicación: 2023-05-12)

    We documented a hematologic patient with prolonged SARS-CoV-2 viral replication in whom emergence of viral mutations was documented after the consecutive use of antivirals and convalescent plasma. The virus detected in the ...

    Distress respiratorio neonatal 

    Pastor Durán, Xavier (Fecha de publicación: 2014-11-04)

    PROTOCOLOS TERAPÉUTICOS. Distress respiratorio neonatal. El distress respiratorio neonatal puede ser una situación grave que llegue a poner en peligro la vida del recién nacido. 1) Diagnóstico. Es fundamentalmente clínico ...

    Pro-adrenomedullin usefulness in the management of children with community-acquired pneumonia, a preliminary prospective observational study 

    Sardà Sánchez, Marta; Calzada Hernández, Joan; Hernández Bou, Susanna; Claret Teruel, Gemma; Velasco Rodríguez, Jesús; Luaces Cubells, Carles (Fecha de publicación: 2012-09-17)

    BackgroundIn adult population with community acquired pneumonia high levels of pro-adrenomedullin (pro-ADM) have been shown to be predictors of worse prognosis. The role of this biomarker in pediatric patients had not been ...

    Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells 

    Caron, Gersende; Hussein, Mourad; Kulis, Marta; Delaloy, Céline; Chatonnet, Fabrice; Pignarre, Amandine; Avner, Stéphane; Lemarié, Maud; Mahé, Elise A.; Verdaguer Dot, Núria; Queirós, Ana C.; Tarte, Karin; Martín-Subero, José Ignacio; Salbert, Gilles; Fest, Thierry (Fecha de publicación: 2020-02-13)

    Molecular mechanisms underlying terminal differentiation of B cells into plasma cells are major determinants of adaptive immunity but remain only partially understood. Here we present the transcriptional and epigenomic ...

    Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder 

    Pardo, Jèssica; Roura, Ignacio; Montal, Victor; Martín Barceló, Cristina; Oltra González, Javier; Campabadal Delgado, Anna; Bargalló Alabart, Núria; Serradell, Mónica; Mayà Casalprim, Gerard; Montini, Angelica; Gaig, Carles; Pont Sunyer, Claustre; Fortea, Juan; Iranzo, Alex; Junqué i Plaja, Carme, 1955-; Segura i Fàbregas, Bàrbara (Fecha de publicación: 2026-01-21)

    Cortical mean diffusivity (cMD), a marker of cortical microstructural changes in neurodegenerative disorders, remains unexplored in isolated REM sleep behavior disorder (iRBD), a prodromal stage of Lewy body (LB) diseases. ...

    Radiological response to nivolumab in patients with hepatocellular carcinoma: A multicenter analysis of real-life practice 

    Rimola Gibert, Jordi; Da Fonseca, Leonardo G.; Sapena, Victor; Perelló, Chistie; Guerrero, Antonio; Torner Simó, Maria; Pons, Mònica; De la Torre Aláez, Manuel; Calleja Panero, José Luis; Lledó, José L.; Varela, Maria; Mínguez, Beatriz; Sangro, Bruno; Matilla, Ana; Torres, Ferran; Ayuso Colella, Carmen; Bruix Tudó, Jordi; Reig, María; Márquez, Laura (Fecha de publicación: 2023-07-04)

    Background and aims: Immune-checkpoint inhibitors are effective in many advanced tumors. However, there is scarce information regarding the radiological response to these agents in hepatocellular carcinoma outside clinical ...

    Relationship between virulence and resistance among Gram-negative bacteria. 

    Cepas, Virginio; Soto González, Sara M. (Fecha de publicación: 2022-11-10)

    Bacteria present in the human body are innocuous, providing beneficial functions, some of which are necessary for correct body function. However, other bacteria are able to colonize, invade, and cause damage to different ...

    Trends in Cancer Incidence in Maputo, Mozambique, 1991-2008 

    Lorenzoni, Cesaltina; Vilajeliu, Alba; Carrilho, Carla; Ismail, Mamudo Rafik; Castillo, Paola; Augusto, Orvalho; García-Basteiro, Alberto L.; Sidat, Mohsin; Sanjosé Llongueras, Silvia de; Menéndez, Clara; Ordi i Majà, Jaume (Fecha de publicación: 2016-02-04)

    BACKGROUND: Very limited information is available regarding the incidence of cancer in sub-Saharan Africa. We analyzed changes in cancer patterns from 1991 to 2008 in Maputo (Mozambique). ...

    Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification 

    Rodriguez Temporal, David; Alcaide Fernández de Vega, Fernando; Mareković, Ivana; O’Connor, James Anthony; Gorton, Rebecca; Ingen, Jakko van; Bossche, An van den; Héry-Arnaud, Genevieve; Beauruelle, Clémence; Orth-Höller, Dorothea; Palacios Gutiérrez, Juan José; Tudó i Vilanova, Griselda; Bou, Germán; Ceyssens, Pieter-Jan; Garrigó, Montserrat; González Martín, Julián; Greub, Gilbert; Hrabak, Jaroslav; Ingebretsen, André; Mediavilla Gradolph, Maria Concepción; Oviaño, Marina; Palop, Begoña; Pranada, Arthur B.; Quiroga, Lidia; Ruiz Serrano, Maria Jesús; Rodríguez Sánchez, Belén (Fecha de publicación: 2022-02-11)

    The ability of MALDI-TOF for the identification of nontuberculous mycobacteria (NTM) has improved recently thanks to updated databases and optimized protein extraction procedures. Few multicentre studies on the reproducibility ...

    Combination of diffusion tensor and functional magnetic resonance imaging during recovery from the vegetative state 

    Fernández-Espejo, Davinia; Junqué i Plaja, Carme, 1955-; Cruse, Damian; Bernabeu Guitart, Montserrat; Roig-Rovira, Teresa; Fàbregas Julià, Neus; Rivas, Eva; Mercader, José M. (Fecha de publicación: 2010-09-21)

    Background: The rate of recovery from the vegetative state (VS) is low. Currently, little is known of the mechanisms and cerebral changes that accompany those relatively rare cases of good recovery. Here, we combined ...

    Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma 

    Rosich, Laia; Montraveta, Arnau; Xargay i Torrent, Sílvia; López-Guerra, Mónica; Roldán, Jocabed; Aymerich Gregorio, Marta; Salaverria Frigola, Itziar; Beà Bobet, Sílvia M.; Campo Güerri, Elias; Pérez Galán, Patricia; Roué, Gaël; Colomer Pujol, Dolors (Fecha de publicación: 2018-03-27)

    Phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway activation contributes to mantle cell lymphoma (MCL) pathogenesis and drug resistance. Antitumor activity has been observed with mTOR ...

    El papel de los avances médico-técnicos en las conclusiones del Congreso de Milán de 1880. Los primeros audífonos mecánicos. 

    Torres, Begoña (Fecha de publicación: 2015-11-26)

    Es ampliamente conocido que en 1880, en el denominado Congreso de Milán, se prohibió el uso de la lengua de signos para educar a las personas sordas. Sin embargo, no se ha abordado en profundidad lo que sucedía en el mundo ...