Fonaments Clínics: Recent submissions
Now showing items 201-220 of 627
Wirtualny trójwymiarowy model kręgosłupa lędźwiowego
Niniejszy interaktywny model został zbudowany z trójwymiarowych rekonstrukcji obrazów rezonansu magnetycznego człowieka.
Carriage prevalence of Salmonella enterica serotype Typhi in gallbladders of adult autopsy cases from Mozambique
INTRODUCTION: Typhoid fever is an important public health problem in many low-income countries where asymptomatic carriers play an important role in its dissemination. The bacterium ...
Mutational Status of SMAD4 and FBXW7 Affects Clinical Outcome in TP53-Mutated Metastatic Colorectal Cancer
Next-generation sequencing (NGS) provides a molecular rationale to inform prognostic stratification and to guide personalized treatment in cancer patients. Here, we determined the prognostic and predictive value of actionable ...
Humans shape the year-round distribution and habitat use of an opportunistic scavenger
Research focused on evaluating how human food subsidies influence the foraging ecology of scavenger species is scarce but essential for elucidating their role in shaping behavioral patterns, population dynamics, and potential ...
Inhibition of Bacterial and Fungal Biofilm Formation by 675 Extracts from Microalgae and Cyanobacteria
Bacterial biofilms are complex biological systems that are difficult to eradicate at a medical, industrial, or environmental level. Biofilms confer bacteria protection against external factors and antimicrobial treatments. ...
Mortality due to Cryptococcus neoformans and Cryptococcus gattii in low-income settings: an autopsy study.
Cryptococcosis is a major opportunistic infection and is one of the leading causes of death in adults living with HIV in sub-Saharan Africa. Recent estimates indicate that more than 130,000 people may die annually of ...
Cortical thinning over two years after first-episode psychosis depends on age of onset
First-episode psychosis (FEP) patients show structural brain abnormalities at the first episode. Whether the cortical changes that follow a FEP are progressive and whether age at onset modulates these changes remains ...
Complete response under sorafenib in patients with hepatocellular carcinoma: Relationship with dermatologic adverse events.
The clinical benefit of sorafenib in patients with hepatocellular carcinoma (HCC) has been undervalued due to the absence of complete responses, even though patients who develop early dermatologic reactions have shown to ...
TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics
Chronic lymphocytic leukemia is associated with a highly heterogeneous disease course in terms of clinical outcomes and responses to chemoimmunotherapy. This heterogeneity is partly due to genetic aberrations identified ...
Validating a common tick survey method: cloth-dragging and line transects
Cloth-dragging is the most widely-used method for collecting and counting ticks, but there are few studies of its reliability. By using cloth-dragging, we applied a replicated line transects survey method, in two areas in ...
Mastopatía fibroquística
La malaltia fibroquística de la mamella o mastopatia fibroquística és un terme vague que pretén definir clínicament una síndrome constituïda per una nodularitat mamària palpable poc delimitada, d'extensió diversa, freqüentment ...
Neurotoxic/Neuroprotective Effects of Clozapine and the Positive Allosteric Modulator of mGluR2 JNJ-46356479 in Human Neuroblastoma Cell Cultures
Current antipsychotics (APs) effectively control positive psychotic symptoms, mainly by blocking dopamine (DA) D2 receptors, but have little effect on negative and cognitive symptoms. Increased glutamate (GLU) release would ...
Stromal markers of activated tumor associated fibroblasts predict poor survival and are associated with necrosis in non-small cell lung cancer
Objectives: Tumor associated fibroblasts (TAFs) are essential contributors of the progression of non-small cell lung cancer (NSCLC). Most lung TAFs exhibit an activated phenotype characterized by the expression of α-SMA ...
Emergence and spread of carbapenem-resistant Acinetobacter baumannii international clone II and III in Lima, Peru
Carbapenem-resistant Acinetobacter baumannii is the top-ranked pathogen in the World Health Organization priority list of antibiotic-resistant bacteria. It emerged as a global pathogen due to the successful expansion of a ...
Perception and knowledge of the effect of climate change on infectious diseases within the general public: A multinational cross-sectional survey-based study
Infectious diseases are emerging and re-emerging due to climate change. Understanding how climate variability affects the transmission of infectious diseases is important for both researchers and the general public. Yet, ...
Predictive model for atrial fibrillation in hypertensive diabetic patients
Background: Several scores to identify patients at high risk of suffering atrial fibrillation have been developed. Their applicability in hypertensive diabetic patients, however, remains uncertain. Our aim is to develop ...
Resistències als principals fàrmacs antituberculosos, importància, detecció i alteracions genètiques associades.
Anualment es declaren de vuit a nou milions de casos de tuberculosi al món, amb gairebé dos milions de morts. El 10% dels casos són resistents a algun dels fàrmacs. Diferents factors influeixen en les resistències, com el ...
Effectiveness and cost-effectiveness of Improving clinicians' diagnostic and communication Skills on Antibiotic prescribing Appropriateness in patients with acute Cough in primary care in CATalonia (the ISAAC-CAT study): Study protocol for a cluster randomised controlled trial
Background: Despite their marginal benefit, about 60% of acute lower respiratory tract infections (ALRTIs) are currently treated with antibiotics in Catalonia. This study aims to evaluate the effectiveness and efficiency ...
Alteracions del control del cicle cel·lular en neoplàsies humanes
Fins fa poc temps, els mecanismes que portaven un grup de cèl·lules de l'organisme a abandonar el comportament ordenat que caracteritza els teixits dels organismes pluricel·lulars i donar origen al càncer eren desconeguts. ...
Outcomes of corticosteroid therapy in patients with viral community-acquired pneumonia
Aim: The objective of this study was to assess the therapeutic effects of corticosteroids in adult patients hospitalized with viral community-acquired pneumonia. Methods: This is a retrospective analysis of data collected ...
