Fonaments Clínics: Envíos recientes
Mostrando ítems 241-260 de 627
Proteomic profiling of the plasma of Gambian children with cerebral malaria
Background Cerebral malaria (CM) is a severe neurological complication of Plasmodium falciparum infection. A number of pathological findings have been correlated with pediatric CM including sequestration, platelet accumulation, ...
A biomarker approach to syndrome-based treatment of severe childhood illness in malaria-endemic areas
This opinion article deals with the diagnostic clinical challenges faced by clinicians or health care workers in malaria-endemic areas when a severely sick child presents to the clinic with fever, coma or respiratory ...
Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
The diagnosis of synovial amyloidosis is based upon synovial biopsy. Synovial fluid (SF) in seven patients with amyloid arthropathy associated with chronic renal failure undergoing haemodialysis were studied. The SF and ...
Sentinel lymph node detection in early-stage ovarian cancer: a systematic review and meta-analysis
Background: A systematic pelvic and para-aortic lymphadenectomy remains the surgical standard management of early-stage epithelial ovarian cancer. Sentinel lymph node mapping is being investigated as an alternative procedure; ...
Postoperatorio del paciente pediátrico trasplantado renal
El trasplante renal es la modalidad de tratamiento sustitutivo que mejores resultados proporciona a niños afectos de insuficiencia renal crónica terminal, aunque no está exenta de una importante morbilidad y mortalidad. ...
Validation of an electronic frailty index with electronic health records: eFRAGICAP index
Objective: To create an electronic frailty index (eFRAGICAP) using electronic health records (EHR) in Catalunya (Spain) and assess its predictive validity with a two-year follow-up of the outcomes: homecare need, ...
Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells
A model of K-Ras-initiated lung cancer was used to follow the transition of precancerous adenoma to adenocarcinoma. In hypoxic, Tgf-β1-rich interiors of adenomas, we show that adenoma cells divide asymmetrically to produce ...
Protease inhibitor monotherapy is associated with a higher level of monocyte activation, bacterial translocation and inflammation
Introduction Monotherapy with protease-inhibitors (MPI) may be an alternative to cART for HIV treatment. We assessed the impact of this strategy on immune activation, bacterial translocation and inflammation. Methods We ...
Is the effect of cognitive reserve in longitudinal outcomes in first-episode psychoses dependent on the use of cannabis?
Background: Cognitive reserve (CR) is a protective factor against cognitive and functional impairment in first-episode psychosis (FEP). The aim of this study was to evaluate the differences in clinical presentation according ...
Performance of the Xpert MTB/RIF Ultra assay for determining cause of death by tuberculosis in tissue samples obtained by minimally invasive autopsies
An estimated 1.5 million deaths were attributable to TB in 2018.1 However, some uncertainty exists as to the exact global figures, given that approximately 30% of incident cases are not diagnosed, and because of the ...
Diagnóstico prequirúrgico de gliomas difusos en adultos: perspectivas prácticas de radiólogos de Unidades de neurooncología Post-WHO 2021
La Clasificación 2021 de tumores del sistema nervioso central (SNC) por la Organización Mundial de la Salud (OMS) fue acogida con entusiasmo, aunque al principio pudo parecer abrumadora. Con el tiempo, hemos comprendido ...
Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization
Background: We have previously shown that an HIV vaccine regimen including three doses of HIV-modified vaccinia virus Ankara vector expressing HIV-1 antigens from clade B (MVA-B) was safe and elicited moderate and durable ...
Brain metabolism during hallucination-like auditory stimulation in schizophrenia
Auditory verbal hallucinations (AVH) in schizophrenia are typically characterized by rich emotional content. Despite the prominent role of emotion in regulating normal perception, the neural interface between emotion-processing ...
Detección de resistencia a agentes antibacterianos mediante MALDI-TOF espectrometría de masas
En la última década hemos asistido a un notable incremento en el número de cepas aisladas en el medio hospitalario que son productoras de β-lactamasas de espectro extendido (BLEE) o, más recientemente, de carbapenemasas. ...
Device for negative pressure wound therapy in low-resource regions: open-source description and bench test evaluation
Background: Negative (vacuum) pressure therapy promotes wound healing. However, commercially available devices are unaffordable to most potential users in low- and middle-income countries (LMICs), limiting access to many ...
Halo sign in fetal cytomegalovirus infection: cerebral imaging abnormalities and postmortem histopathology in cohort of 35 infected fetuses.
To evaluate the correlation of periventricular echogenic halo (halo sign) with histopathological findings and its association with other brain imaging abnormalities in fetuses with cytomegalovirus (CMV) infection.
Antimicrobial resistance and virulence characterisation among Escherichia coli clinical isolates causing severe obstetric infections in pregnant women
The virulence markers and the antimicrobial resistance profile of 78 Escherichia coli isolates causing obstetric infections accompanied or not by sepsis were studied. Adhesion-related virulence factors were the most ...
Telemática y Pediatría
Se define como telemática aquel apartado de la Ciencia que estudia la comunicación en su versión más amplia. La expansión de sus aplicaciones es progresiva, de forma exponencial, y la razón fundamental de dicho fenómeno ...
Association between confocal morphologic classification and clinical phenotypes of multiple primary and familial melanomas
Importance: The improved knowledge of clinical, morphologic, and epidemiologic heterogeneity of melanoma in the context of multiple primary and familial melanomas may improve prevention, diagnosis, and prognosis of melanoma. ...
Spread of ST348 Klebsiella pneumoniae producing NDM-1 in a peruvian hospital
The aim of this study was to characterize carbapenem-resistant Klebsiella pneumoniae (CR-Kp) isolates recovered from adults and children with severe bacteremia in a Peruvian Hospital in June 2018. Antimicrobial susceptibility ...
