dc.contributor
Universitat Ramon Llull. IQS
dc.contributor.author
Cosialls, Raúl
dc.contributor.author
Simó, Cristina
dc.contributor.author
Borrós, Salvador
dc.contributor.author
Gómez Vallejo, Vanessa
dc.contributor.author
Schmidt, Claudia
dc.contributor.author
Llop, Jordi
dc.contributor.author
Cuenca, Ana B.
dc.contributor.author
Casini, Angela
dc.date.issued
2023-01-12
dc.identifier.issn
1521-3765
dc.identifier.uri
http://hdl.handle.net/20.500.14342/4695
dc.description.abstract
To advance the design of self-assembled metallosupramolecular architectures as new generation theranostic agents, the synthesis of 18F-labelled [Pd2L4]4+ metallacages is reported. Different spectroscopic and bio-analytical methods support the formation of the host-guest cage-cisplatin complex. The biodistribution profiles of one of the cages, alone or encapsulating cisplatin have been studied by PET/CT imaging in healthy mice in vivo, in combination to ICP-MS ex vivo.
dc.relation.ispartof
Chemistry – A European Journal 2023, 29(3), e202202604
dc.rights
Attribution 4.0 International
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Ammonium trifluoroborates
dc.subject
Medicaments--Modes d'administració
dc.title
PET Imaging of Self-Assembled 18F-Labelled Pd2L4 Metallacages for Anticancer Drug Delivery
dc.type
info:eu-repo/semantics/article
dc.description.version
info:eu-repo/semantics/publishedVersion
dc.relation.projectID
info:eu-repo/grantAgreement/MCI/PN I+D/PID2020-113661GB-I00
dc.relation.projectID
info:eu-repo/grantAgreement/SUR del DEC/SGR/2017 SGR 01051
dc.relation.projectID
info:eu-repo/grantAgreement/SUR del DEC/SGR/2017 SGR 00294
dc.relation.projectID
info:eu-repo/grantAgreement/MCI/PN I+D/PID2020-117656RB-I00
dc.identifier.doi
https://doi.org/10.1002/chem.202202604
dc.rights.accessLevel
info:eu-repo/semantics/openAccess
