dc.contributor.author |
Biosca, Maria |
dc.contributor.author |
de la Cruz-Sánchez, Pol |
dc.contributor.author |
Faiges, Jorge |
dc.contributor.author |
Margalef, Jèssica |
dc.contributor.author |
Salomó, Ernest |
dc.contributor.author |
Riera, Antoni |
dc.contributor.author |
Verdaguer, Xavier |
dc.contributor.author |
Ferré, Joan |
dc.contributor.author |
Maseras, Feliu |
dc.contributor.author |
Besora, Maria |
dc.contributor.author |
Pàmies, Oscar |
dc.contributor.author |
Diéguez, Montserrat |
dc.date.accessioned |
2023-04-18T13:10:28Z |
dc.date.available |
2024-02-14T01:45:05Z |
dc.date.issued |
2023-02-14 |
dc.identifier.uri |
http://hdl.handle.net/2072/532941 |
dc.format.extent |
46 p. |
dc.language.iso |
eng |
dc.publisher |
ACS Publications |
dc.rights |
Creative Commons Attribution-NonCommercial-NoDerivs License, |
dc.source |
RECERCAT (Dipòsit de la Recerca de Catalunya) |
dc.subject.other |
Química |
dc.title |
P-Stereogenic Ir-MaxPHOX: A Step toward Privileged Catalysts for Asymmetric Hydrogenation of Nonchelating Olefins |
dc.type |
info:eu-repo/semantics/article |
dc.type |
info:eu-repo/semantics/acceptedVersion |
dc.subject.udc |
00 - Ciència i coneixement. Investigació. Cultura. Humanitats |
dc.embargo.terms |
12 mesos |
dc.relation.projectID |
FEDER/Ministerio de Ciencia e Innovación (MICINN)/AEI (PID2019-104904GB-I00, PID2021-128128NB-100, PID2020-115074GB-I00, PID2020-112825RB-I00 and CEX2019-000925-S) |
dc.relation.projectID |
Grant 2017SGR1472 funded by the Catalan Government |
dc.relation.projectID |
CERCA Program of the Catalan Government |
dc.identifier.doi |
10.1021/acscatal.2c05579 |
dc.rights.accessLevel |
info:eu-repo/semantics/openAccess |
dc.description.abstract |
The Ir-MaxPHOX-type catalysts demonstrated high catalytic performance in the hydrogenation of a wide range of nonchelating olefins with different geometries, substitution patterns, and degrees of functionalization. These air-stable and readily available catalysts have been successfully applied in the asymmetric hydrogenation of di-, tri-, and tetrasubstituted olefins (ee′s up to 99%). The combination of theoretical calculations and deuterium labeling experiments led to the uncovering of the factors responsible for the enantioselectivity observed in the reaction, allowing the rationalization of the most suitable substrates for these Ir-catalysts. |