Biofunctionalization of patterned PLLA surfaces with RGD, REDV and YIGSR peptides to promote endothelial cells adhesion and migration

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dc.contributor	Universitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
dc.contributor	Universitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
dc.contributor	Universität des Saarlandes
dc.contributor.author	Schieber, Tiabo A.
dc.contributor.author	Mas Moruno, Carlos
dc.contributor.author	Gil Mur, Francisco Javier
dc.contributor.author	Mücklich, F.
dc.contributor.author	Pegueroles Neyra, Marta
dc.date	2016
dc.identifier.citation	Schieber, T.A., Mas-Moruno, C., Gil, J., Mücklich, F., Pegueroles, Marta. Biofunctionalization of patterned PLLA surfaces with RGD, REDV and YIGSR peptides to promote endothelial cells adhesion and migration. A: European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society. "European Cells and Materials". Uppsala: 2016.
dc.identifier.citation	1473-2262
dc.identifier.uri	http://hdl.handle.net/2117/101583
dc.language.iso	eng
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subject	Àrees temàtiques de la UPC::Enginyeria dels materials
dc.subject	Peptides
dc.subject	Pèptids
dc.title	Biofunctionalization of patterned PLLA surfaces with RGD, REDV and YIGSR peptides to promote endothelial cells adhesion and migration
dc.type	info:eu-repo/semantics/publishedVersion
dc.type	info:eu-repo/semantics/conferenceObject
dc.description.abstract	Angioplasty and stent implantation open the blocked artery and restore proper blood flow after atherosclerosis disease. Despite their utility, intracoronary stents induce two types of complications: in-stent restenosis and thrombosis. Recently, biodegradable poly-L-lactic acid (PLLA) stents have been inserted to restore the healed artery, reabsorb and consequently avoid late stent thrombosis [1]. Moreover, rapid stent endothelialisation is one of the main goals in order to heal the damaged tissue and decrease in-stent restenosis [2]. The present work combines topographical modification and peptide functionalization of PLLA surfaces to increase endothelial cells adhesion and migration, and thus enhance endothelialization.

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