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Identification of intracellular calcium dynamics in stimulated cardiomyocytes
Vallmitjana Lees, Alex; Barriga, Montserrat; Nenadic, Zoran; Llach, Anna; Álvarez Lacalle, Enrique; Hove-Madsen, Leif; Benítez Iglesias, Raúl
Universitat Politècnica de Catalunya. Departament de Física Aplicada; Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial; Universitat Politècnica de Catalunya. NOLIN - Física No-Lineal i Sistemes Fora de l´Equilibri
We have developed an automatic method for the analysis and identification of dynamical regimes in intracellular calcium patterns from confocal calcium images. The method allows the identification of different dynamical patterns such as spatially concordant and discordant alternans, irregular behavior or phase-locking regimes such as period doubling or halving. The method can be applied to the analysis of different cardiac pathologies related to anomalies at the cellular level such as ventricular reentrant arrhythmias.
Peer Reviewed
Intracellular calcium
Medical image processing
Processament digital -- Biomedicina
Calci en l'organisme
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
IEEE Press. Institute of Electrical and Electronics Engineers
         

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