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Mostrando ítems 1-20 de 439649
Validation and selection of criteria for evaluating apps for managing depression: a Delphi study
Delphi Technique; Depression & mood disorders; eHealth
Optimizing early-phase immunotherapy trials: the role of biomarker enrichment strategies
Biomarker; Drug response biomarkers; Early-phase trials
Selection of initiatives to improve the management of patients with hereditary angioedema by the hospital pharmacy using the nominal group technique
Al·lèrgia; Servei de farmàcia; Qualitat de l'atenció sanitària
First-in-Human, Phase I/II Dose Escalation and Expansion Study of Zelenectide Pevedotin in Patients With Advanced Solid Tumors: Results From Monotherapy Dose Escalation
Advanced solid tumors; Monotherapy dose escalation
Food allergy severity across the world: A World Allergy Organization international survey
Anaphylaxis; Economics; Epidemiology
No innocent bystanders: pertussis vaccination and evolutionary parallelisms between Bordetella parapertussis and Bordetella pertussis
Bordetella parapertussis; Phylogenetic diversity; Vaccine driven evolution
Evaluation of autonomic dysfunction in hereditary transthyretin amyloidosis
Amyloidosis; Transthyretin; Dysautonomia
Frailty and sarcopenia metabolomic signatures in kidney transplant candidates: the FRAILMar study
Background. Sarcopenia and frailty are often overlooked in assessing kidney transplant (KT) candidates with chronic kidney disease (CKD), potentially leading to poor post-transplant outcomes. This study aimed to identify ...
Does plate fixation improve the Latarjet procedure for anterior glenohumeral instability?
Article disponible en castellà: https://hdl.handle.net/10230/72582
Allergic contact dermatitis in adults with and without atopic dermatitis: Evaluation of the Spanish Contact Dermatitis Registry (REIDAC)
Background: Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are inflammatory skin conditions whose association is not clearly defined. Objectives: To identify differences in ACD profile between patients with ...
Loss-of-function Gαs rare disease variants exert mutation-specific effects on GPCR signaling
G protein-coupled receptors (GPCRs) are transmembrane detectors of extracellular signals that activate heterotrimeric G proteins to regulate intracellular responses. Because there are only 16 Gα proteins that can couple ...
Asymptomatic inflammatory bowel disease diagnosed during colorectal cancer population screening in Catalonia: characteristics and natural history
Introduction: Inflammatory bowel disease (IBD) is usually diagnosed when symptomatic. Prognosis and evolution of preclinical IBD is largely unknown. However, colorectal cancer screening programs (CRCSP) detect a subset of ...
Índice ECoTES de desempeño del sistema de seguridad y salud en el trabajo, resultados de un estudio piloto en seis países iberoamericanos
Objective: To describe and evaluate the methodology of the ECoTES index, after its implementation in a pilot study in six Ibero-American countries. The ECoTES index (Spanish acronym for surveys of working conditions, ...
Serum vitamin B12 concentration is associated with improved memory in older individuals with higher adherence to the Mediterranean diet
Background & aims: Vitamin B12 plays a crucial role in cognition, but its effect might be regulated by the presence of other micronutrients, such as folate. The aim was to evaluate the effects of vitamin B12 on cognitive ...
Mapping the perceived importance of actors in social policy accountability across welfare state regimes: an assessment made by academic experts
This article examines the role of a range of actors in social policy accountability across different welfare regimes, with a focus on Austria, Denmark, Switzerland, and Spain. Using a survey conducted with academic experts ...
Development of SOCS1 mimetics as novel approach to harmonize inflammation, oxidative stress, and fibrogenesis in metabolic dysfunction-associated steatotic liver disease
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic liver disease, encompassing a spectrum from simple steatosis to steatohepatitis (MASH), cirrhosis, and hepatocellular ...
Curs de pragmàtica: una introducció a l'estudi del significat en context
Com indica el títol, aquest llibre té com a objectiu oferir una introducció al camp de la pragmàtica, l'estudi del significat lingüístic en context. Està pensat principalment per a estudiants de grau o de màster en ...
The piper at the gates of brain: A systematic review of surface modification strategies on lipid nanoparticles to overcome the Blood-Brain-Barrier
The Blood-Brain Barrier (BBB) significantly impedes drug delivery to the central nervous system. Nanotechnology, especially surface-functionalized lipid nanoparticles, offers innovative approaches to overcome this barrier. ...
Exploration of moisture activated dry granulation for the development of gastroretentive tablets aided by SeDeM diagram
Moisture activated dry granulation (MADG) is an attractive granulation process. However, only a few works have explored modified drug release achieved by MADG, and to the best of the authors knowledge, none of them have ...
Quantisation of LLMs on modern CPU architectures
The rapid growth of large language models (LLMs) has intensified the demand for efficient training and inference solutions. While GPUs dominate this domain, their cost, power consumption, and limited availability motivate ...
