Orthogonal protecting groups in the synthesis of tryptophanyl-hexahydropyrroloindoles

dc.contributor.author
Ruiz Sanchis, Pau
dc.contributor.author
Savina, Svetlana A.
dc.contributor.author
Acosta, Gerardo A.
dc.contributor.author
Albericio Palomera, Fernando
dc.contributor.author
Álvarez Domingo, Mercedes
dc.date.issued
2014-06-02T08:10:38Z
dc.date.issued
2021-11-01T06:10:14Z
dc.date.issued
2011-11-22
dc.date.issued
2014-05-30T11:35:20Z
dc.identifier
1434-193X
dc.identifier
https://hdl.handle.net/2445/54707
dc.identifier
598515
dc.description.abstract
The synthesis of various polycyclic systems containing a C3a-Ni bond between a hexahydropyrrolo[2,3-b]indole and an indole tryptophan is described here. A series of experiments were performed to determine the best combination of five orthogonal protecting groups and the best reaction conditions for formation of said bond, which is a common feature among many recently discovered marine natural products.
dc.format
7 p.
dc.format
application/pdf
dc.format
application/pdf
dc.language
eng
dc.publisher
Wiley-VCH
dc.relation
Versió preprint del document publicat a: http://dx.doi.org/10.1002/ejoc.201101057
dc.relation
European Journal of Organic Chemistry, 2012, vol. 2012, num. 1, p. 67-73
dc.relation
http://dx.doi.org/10.1002/ejoc.201101057
dc.rights
(c) Wiley-VCH Verlag GmbH & Co. KGaA, 2012
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Productes naturals marins
dc.subject
Química heterocíclica
dc.subject
Aminoàcids
dc.subject
Síntesi de pèptids
dc.subject
Marine natural products
dc.subject
Heterocyclic chemistry
dc.subject
Amino acids
dc.subject
Peptide synthesis
dc.title
Orthogonal protecting groups in the synthesis of tryptophanyl-hexahydropyrroloindoles
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/submittedVersion


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