dc.contributor.author
Whitaker, Hayley C.
dc.contributor.author
Kote-Jarai, Zsofia
dc.contributor.author
Ross-Adams, Helen
dc.contributor.author
Warren, Anne Y.
dc.contributor.author
Burge, Johanna
dc.contributor.author
George, Anne
dc.contributor.author
Bancroft, Elizabeth K.
dc.contributor.author
Jhavar, Sameer
dc.contributor.author
Leongamornlert, Daniel
dc.contributor.author
Tymrakiewicz, Malgorzata
dc.contributor.author
Saunders, Edward J.
dc.contributor.author
Page, Elizabeth
dc.contributor.author
Mitra, Anita
dc.contributor.author
Mitchell, Gillian
dc.contributor.author
Lindeman, Geoffrey J.
dc.contributor.author
Evans, D. Gareth
dc.contributor.author
Blanco Guillermo, Ignacio
dc.contributor.author
Mercer, Catherine
dc.contributor.author
Rubinstein, Wendy S.
dc.contributor.author
Neal, David E.
dc.date.issued
2013-06-26T18:13:28Z
dc.date.issued
2013-06-26T18:13:28Z
dc.date.issued
2010-10-13
dc.date.issued
2013-06-26T18:13:28Z
dc.identifier
https://hdl.handle.net/2445/44444
dc.description.abstract
Microseminoprotein-beta (MSMB) regulates apoptosis and using genome-wide association studies the rs10993994 single nucleotide polymorphism in the MSMB promoter has been linked to an increased risk of developing prostate cancer. The promoter location of the risk allele, and its ability to reduce promoter activity, suggested that the rs10993994 risk allele could result in lowered MSMB in benign tissue leading to increased prostate cancer risk.
dc.format
application/pdf
dc.publisher
Public Library of Science (PLoS)
dc.relation
Reproducció del document publicat a: 10.1371/journal.pone.0013363
dc.relation
PLoS One, 2010, vol. 5, num. 10, p. e13363
dc.relation
http://dx.doi.org/10.1371/journal.pone.0013363
dc.rights
cc-by (c) Whitaker, Hayley C. et al., 2010
dc.rights
http://creativecommons.org/licenses/by/3.0/es
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Patologia i Terapèutica Experimental)
dc.subject
Càncer de pròstata
dc.subject
Marcadors genètics
dc.subject
Prostate cancer
dc.subject
Genetic markers
dc.title
The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
