Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline

dc.contributor.author
Amat Tusón, Mercedes
dc.contributor.author
Ramos, Carlos
dc.contributor.author
Pérez Bosch, Maria
dc.contributor.author
Molins i Grau, Elies
dc.contributor.author
Florindo, Pedro
dc.contributor.author
Santos, Maria M. M.
dc.contributor.author
Bosch Cartes, Joan
dc.date.issued
2013-04-30T10:52:01Z
dc.date.issued
2014-03-07T23:02:13Z
dc.date.issued
2013-03-07
dc.date.issued
2013-04-29T15:13:30Z
dc.identifier
1359-7345
dc.identifier
https://hdl.handle.net/2445/36425
dc.identifier
620577
dc.description.abstract
Starting from (S)-tryptophanol, a formal synthesis of ent-rhyncho-phylline and ent-isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and alkylation reactions, and the final adjustment of the oxidation level at the oxindole and piperidine moieties, is reported.
dc.format
3 p.
dc.format
application/pdf
dc.format
application/pdf
dc.language
eng
dc.publisher
Royal Society of Chemistry
dc.relation
Versió postprint del document publicat a: http://dx.doi.org/10.1039/c2cc38540f
dc.relation
Chemical Communications, 2013, vol. 49, num. 19, p. 1954-1956
dc.relation
http://dx.doi.org/10.1039/c2cc38540f
dc.rights
(c) Amat Tusón, Mercedes et al., 2013
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Alcaloides
dc.subject
Síntesi asimètrica
dc.subject
Estereoquímica
dc.subject
Alkaloids
dc.subject
Asymmetric synthesis
dc.subject
Stereochemistry
dc.title
Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion


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