dc.contributor.author
Amat Tusón, Mercedes
dc.contributor.author
Pérez Bosch, Maria
dc.contributor.author
Minaglia, Annamaria Tania
dc.contributor.author
Casamitjana i Badia, Núria
dc.contributor.author
Bosch Cartes, Joan
dc.date.issued
2013-04-15T16:48:33Z
dc.date.issued
2013-04-15T16:48:33Z
dc.date.issued
2005-07-25
dc.date.issued
2013-04-15T16:48:33Z
dc.identifier
https://hdl.handle.net/2445/34586
dc.description.abstract
An enantioselective route to cis-perhydroisoquinolines, involving a cyclocondensation reaction of (R)-phenylglycinol with a racemic oxoester, a stereoselective conjugate addition to an unsaturated bicyclic lactam, and the closure of the carbocyclic ring by a ring-closing metathesis as the key steps is reported. This route allows the preparation of 3-cyano derivatives as well as cis-octahydroisoquinolines bearing a quaternary center at the C4-position.
dc.format
application/pdf
dc.publisher
American Chemical Society
dc.relation
Versió postprint del document publicat a: http://dx.doi.org/10.1021/ol051242c
dc.relation
Organic Letters, 2005, vol. 7, num. 17, p. 3653-3656
dc.relation
http://dx.doi.org/10.1021/ol051242c
dc.rights
(c) American Chemical Society , 2005
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.title
An enantioselective entry to cis-perhydroisoquinolines
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
