Study of quality controls for stability check of the ROIs of a ketones mixture in different GC-IMS measurement campaigns

Abstract

GC-IMS is a very good complementary technique to traditional GC-MS, that presents some advantages, but also, some disadvantages such as misalignments produced by many parameters affecting the equipment stability. The reproducibility of the measures has been studied in two different measurement campaigns with a set of automatized quality control parameters. Figures of merit from one region of interest present in the samples show that the saturation and asymmetry do not change between measurement campaigns, but the volume and area of the total ion spectra change. A correction of these changes between batches should be developed.