A Novel, Extremely Bioavailable Cocrystal of Pterostilbene

dc.contributor.author
Bofill, Lídia
dc.contributor.author
Barbas Cañero, Rafael
dc.contributor.author
Sande, Dafne de
dc.contributor.author
Font Bardia, Ma. Mercedes
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Ràfols Llach, Clara
dc.contributor.author
Albertí, Joan
dc.contributor.author
Prohens López, Rafael
dc.date.issued
2022-02-25T10:57:52Z
dc.date.issued
2022-03-03T06:10:26Z
dc.date.issued
2021-03-03
dc.date.issued
2022-02-25T10:57:52Z
dc.identifier
1528-7483
dc.identifier
https://hdl.handle.net/2445/183529
dc.identifier
710755
dc.description.abstract
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats, which converts the new cocrystal into a very promising candidate for new formulations of pterostilbene with improved performance.
dc.format
27 p.
dc.format
application/pdf
dc.language
eng
dc.publisher
American Chemical Society
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.0c01716
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Crystal Growth & Design, 2021, vol. 21, num. 4, p. 2315-2323
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https://doi.org/10.1021/acs.cgd.0c01716
dc.rights
(c) American Chemical Society , 2021
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)
dc.subject
Cristal·lografia
dc.subject
Crystallography
dc.title
A Novel, Extremely Bioavailable Cocrystal of Pterostilbene
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion


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