2022-02-25T10:57:52Z
2022-03-03T06:10:26Z
2021-03-03
2022-02-25T10:57:52Z
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats, which converts the new cocrystal into a very promising candidate for new formulations of pterostilbene with improved performance.
Article
Accepted version
English
American Chemical Society
Versió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.0c01716
Crystal Growth & Design, 2021, vol. 21, num. 4, p. 2315-2323
https://doi.org/10.1021/acs.cgd.0c01716
(c) American Chemical Society , 2021