dc.contributor.author
Amat Tusón, Mercedes
dc.contributor.author
Llor Brunés, Núria
dc.contributor.author
Subrizi, Fabiana
dc.contributor.author
Pérez Bosch, Maria
dc.contributor.author
Molins i Grau, Elies
dc.contributor.author
Bosch Cartes, Joan
dc.date.issued
2020-11-04T09:06:16Z
dc.date.issued
2020-11-04T09:06:16Z
dc.date.issued
2020-11-04T09:06:16Z
dc.identifier
https://hdl.handle.net/2445/171749
dc.description.abstract
Cyclization of the lactam carbonyl on the indole ring in tryptophanol-derived oxazolopiperidone lactams 2 and 6, under the classical POCl3-promoted Bischler-Napieralski conditions and under neutral conditions via the corresponding thiolactam, has been studied. Whereas tricyclic lactam 2 only leads to products coming from an α-amidoalkylation process, bicyclic lactam 6 undergoes cyclization on the lactam carbonyl, leading to the expected indolo[2,3-a]quinolizidine derivatives.
dc.format
application/pdf
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1002/ejoc.200
dc.relation
European Journal of Organic Chemistry, 2013, p. 1246-1252
dc.relation
https://doi.org/10.1002/ejoc.200
dc.rights
(c) Wiley-VCH, 2013
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Compostos heterocíclics
dc.subject
Síntesi orgànica
dc.subject
Heterocyclic compounds
dc.subject
Organic synthesis
dc.title
Studies on the Regioselectivity of the Cyclization of Tryptophanol-Derived Oxazolopiperidone Lactams
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
