Facile synthesis of azocino[4,3-b]indoles by ring-closing metathesis

dc.contributor.author
Bennasar Fèlix, M. Lluïsa
dc.contributor.author
Zulaica Gallego, Ester
dc.contributor.author
Solé Arjó, Daniel
dc.contributor.author
Alonso Serrano, Sandra
dc.date.issued
2020-05-15T09:12:08Z
dc.date.issued
2020-05-15T09:12:08Z
dc.date.issued
2007-01
dc.date.issued
2020-05-15T09:12:08Z
dc.identifier
0040-4020
dc.identifier
https://hdl.handle.net/2445/160425
dc.identifier
555923
dc.description.abstract
The azocino[4,3-b]indole system, tricyclic substructure of the indole alkaloids apparicine and ervaticine, is efficiently assembled by ring-closing metathesis of 2-allyl-3-(allylaminomethyl)indoles. The metathesis sites are introduced into the indole nucleus by reductive amination of a 3-formyl derivative with allylamine, followed by a-lithiation with subsequent electrophilic trapping with acrolein.
dc.format
6 p.
dc.format
application/pdf
dc.language
eng
dc.publisher
Elsevier B.V.
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1016/j.tet.2006.11.043
dc.relation
Tetrahedron, 2007, vol. 63, num. 4, p. 861-866
dc.relation
https://doi.org/10.1016/j.tet.2006.11.043
dc.rights
(c) Elsevier B.V., 2007
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Alcaloides
dc.subject
Metàtesi (Química)
dc.subject
Síntesi orgànica
dc.subject
Alkaloids
dc.subject
Metathesis (Chemistry)
dc.subject
Organic synthesis
dc.title
Facile synthesis of azocino[4,3-b]indoles by ring-closing metathesis
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)