Aplicació terapèutica dels compostos organometal·lics

Abstract

In recent years, organometallic chemistry has acquired an important role in clinical practice, although it exists a wide variety of organic structures linked to metals in nature, and involved in biological processes. The most commonly used metals in therapy are Fe, Ag and Au even though studies with other metals, such as Ru and Rh, are increasing. The organometallic compounds have been evaluated as chemotherapeutic, antibacterial agents, radioimaging and fluorescence agents, among other applications. Ferrocene derivatives or N-heterocyclic carbenes (NHC) are structures with greater potential in these areas. This work is a review of the applications of organometallic compounds families and is highlighted the features from those that have stood out in their application field.