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Multicomponent reaction access to complex quinolines via oxidation of the povarov adducts

Author

Vicente García, Esther

Ramón, Rosario

Preciado Gallego, Sara

Lavilla Grífols, Rodolfo

Publication date

2018-03-08T14:32:18Z

2018-03-08T14:32:18Z

2011

2018-03-08T14:32:18Z

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Abstract

The tetrahydroquinolines obtained through the Povarov multicomponent reaction have been oxidized to the corresponding quinoline, giving access to a single product through a two-step sequence. Several oxidizing agents were studied and manganese dioxide proved to be the reagent of choice, affording higher yields, cleaner reactions and practical protocols.

Document Type

Article

Published version

Language

English

Subjects and keywords

Quinoleïna; Oxidació; Síntesi orgànica; Quinoline; Oxidation; Organic synthesis

Publisher

Beilstein Institute

Related items

Reproducció del document publicat a: https://doi.org/10.3762/bjoc.7.110

Beilstein Journal of Organic Chemistry, 2011, vol. 7, p. 980-987

https://doi.org/10.3762/bjoc.7.110

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DIDL MARC MARC_CCUC METS OAI_DC ORE QDC RDF

Rights

cc-by (c) Vicente García, Esther et al., 2011

http://creativecommons.org/licenses/by/3.0/es

This item appears in the following Collection(s)

Farmacologia, Toxicologia i Química Terapèutica [675]

ISGlobal - Institut de Salut Global de Barcelona [60793]