dc.contributor.author
Ghirardi, Elena
dc.contributor.author
Griera Farres, Rosa
dc.contributor.author
Piccichè, Miriam
dc.contributor.author
Molins i Grau, Elies
dc.contributor.author
Fernández Cadenas, Israel
dc.contributor.author
Bosch Cartes, Joan
dc.contributor.author
Amat Tusón, Mercedes
dc.date.issued
2017-03-07T14:56:07Z
dc.date.issued
2017-11-18T23:01:26Z
dc.date.issued
2016-11-18
dc.date.issued
2017-03-07T14:56:07Z
dc.identifier
https://hdl.handle.net/2445/108046
dc.description.abstract
Cyclocondensation of (R)-phenylglycinol with stereoisomeric mixtures (racemates, cis/trans) of 3-substituted 2- oxocyclohexaneacetates stereoselectively afforded tricyclic oxazoloindolone lactams, from which straightforward procedures for the stereocontrolled formation of enantiopure 7-substituted octahydroindoles with a variety of stereochemical patterns have been developed. The methodology has been successfully applied to the synthesis of (+)-α-lycorane.
dc.format
application/pdf
dc.format
application/pdf
dc.publisher
American Chemical Society
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.6b02861
dc.relation
Organic Letters, 2016, vol. 18, num. 22, p. 5836-5839
dc.relation
https://doi.org/10.1021/acs.orglett.6b02861
dc.rights
(c) American Chemical Society , 2016
dc.rights
info:eu-repo/semantics/openAccess
dc.source
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject
Síntesi asimètrica
dc.subject
Asymmetric synthesis
dc.title
Stereocontrolled access to enantiopure to enantiopure 7-substituted cis- and trans-octahydroindoles
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/acceptedVersion
