Development of diagnostics for Chagas disease: where should we put our limited resources?

Abstract

According to the World Health Organization (WHO), one of the milestones set by the London Declaration for Chagas disease the interruption of Chagas disease transmission through blood transfusion in Latin America was achieved in most countries (20 out of 21) in 2015. This is a crucial step towards reaching the goal of controlling Chagas disease by 2020. However, many challenges remain: less than 1% of the 6 to 7 million people infected with Trypanosoma cruzi are treated, and new infections still occu