Química Inorgànica i Orgànica: Enviaments recents
Ara mostrant els elements 41-60 de 978
Effect of pressure on La2(WO4)3 with a modulated scheelite-type structure
We have studied the effect of pressure on the structural and vibrational properties of lanthanum tritungstate La2(WO4)3. This compound crystallizes under ambient conditions in the modulated scheelite-type structure known ...
New Potent Inhibitor of Transforming Growth Factor-Beta (TGFβ) Signaling that is Efficacious against Microsatellite Stable Colorectal Cancer Metastasis in Combination with Immune Checkpoint Therapy in Mice
Blockade of the TGFβ signaling pathway has emerged from preclinical studies as a potential treatment to enhance the efficacy of immune checkpoint inhibition in advanced colorectal cancer (CRC) and several other types of ...
Polyurethane-polyurea hybrid nanocapsules as efficient delivery systems of anticancer Ir(III) metallodrugs
Cyclometalated Ir(III) complexes hold great promise as an alternative to platinum metallodrugs for the therapy and diagnosis of cancer. However, their low aqueous solubility and poor cell membrane permeability are obstacles ...
Facile morphology control of gold(0) structures from aurophilic assemblies
Different gold microstructures have been synthesized by using supramolecular gold(I) organometallic compounds as templates and Ag nanoparticles as reducing agent. The use of fibers resulting from supramolecular assemblies ...
Mitochondria-Targeted COUPY Photocages: Synthesis and Visible-Light Photoactivation in Living Cells
Releasing bioactive molecules in specific subcellular locations from the corresponding caged precursors offers great potential in photopharmacology, especially when using biologically compatible visible light. By taking ...
Dynamic nuclear polarization using polychlorotriphenylmethyl radicals reveals supramolecular polarization transfer effects
Polychlorinated trityl radicals (see structure: C black, Cl green, Na gray, O red) used for dynamic nuclear polarization (DNP) showed a new transfer mechanism involving quadrupolar chlorine nuclei. The observation of ...
Au(I) complex-titania hybrid photocatalyst for hydrogen production
Integration of TiO2 and an Au(I) complex containing a thiocoumarin moiety results in a very efficient photocatalyst for the generation of H2. The molecular structure of the complex is preserved under photoreaction due to ...
Single-ion magnetic anisotropy in a vacant octahedral Co(II) complex
The first example of a pentacoordinate CoII single-ion magnet based on a P-donor ligand with vacant octahedral coordination geometry is reported here. Thorough magnetic measurements reveal the presence of field induced ...
Slow magnetic relaxation and luminescence properties in b-diketonate lanthanide(III)complexes. Preparation of Eu(III) and Yb(III) OLED devices
La reacció de [Ln(btfa)₃(H₂O)₂] (btfa⁻ = 4,4,4-trifluoro-1-fenil-1,3-butanodionat) amb 4,4'-dinonil-2,2'-bipiridil (4,4'-dinonilbipy) en etanol permet l’aïllament de complexos mononuclears [Ln(btfa)₃(4,4'-dinonilbipy)], ...
Molecular basis or arginine and lysine DNA sequence-dependent thermo-stability modulation
We have used a variety of theoretical and experimental techniques to study the role of four basic amino acids-Arginine, Lysine, Ornithine and L-2,4-Diaminobutyric acid-on the structure, flexibility and sequence-dependent ...
A three-protein charge zipper stabilizes a protein complex modulating bacterial gene silencing
The Hha/YmoA nucleoid-associated proteins help selectively silence horizontally acquired genetic material, including pathogenicity and antibiotic resistance genes and their maintenance in the absence of selective pressure. ...
Six states switching of redox-active molecular tweezers by three orthogonal stimuli
A six level molecular switch based on terpyridine(Ni-salphen)(2) tweezers and addressable by three orthogonal stimuli (metal coordination, redox reaction, and guest binding) is reported. By a metal coordination stimulus, ...
Rhodium(I) macrocyclic and cage-like structures containing diphosphine bridging ligands
Three series of rhodium organometallic complexes, mono- (1c, 2c, 5c, 6c), di- (1a-6a) and tetranuclear (1b, 5b, 6b), containing six different diphosphines (1,1'- bis(diphenylphosphino)methane or dppm (1), 1,2-bis(dipheny ...
Enantioselective Synthesis of β-Methyl Amines via Iridium-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Allyl Amines.
The iridium-catalyzed asym. hydrogenation of several N-sulfonyl allyl amines was reported. All substrates could be easily obtained by the Ir-catalyzed isomerization of N-tosylaziridines reported previously. The com. available ...
Enantioselective preparation of delta-valerolactones using horse liver alcohol dehydrogenase
Horse liver alcohol dehydrogenase (HLADH) has been found to be a versatile biocatalyst for the desymmetrization of prochiral 3‐arylpentane‐1,5‐diols, based on a two‐step one‐pot oxidation. This procedure has allowed the ...
Exploiting metallophilicity for the assembly of inorganic nanocrystals and conjugated organic molecules
The accurate engineering of interfaces between inorganic nanocrystals and semiconducting organic molecules is currently viewed as key for further developments in critical fields such as photovoltaics and photocatalysis. ...
Origin of the large dispersion of magnetic properties in nanostructured oxides: FexO/Fe3O4 nanoparticles as a case study
The intimate relationship between stoichiometry and physicochemical properties in transition-metal oxides makes them appealing as tunable materials. These features become exacerbated when dealing with nanostructures. ...
Direct and enantioselective aldol reactions catalyzed by chiral nickel(II) complexes
A direct and asymmetric aldol reaction of N-acylthiazinanethiones with aromatic aldehydes catalyzed by chiralnickel(II) complexes is reported. The reaction gives thecorresponding O-TIPS-protected anti-aldol adducts in ...
SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules
Antiviral agents are needed for the treatment of SARS-CoV-2 infections and to control other coronavirus outbreaks that may occur in the future. Here we report the identification and characterization of RNA-binding compounds ...
Structural Characterization, Magnetic and Luminescent Properties of Praseodymium(III)‐4,4,4‐Trifluoro‐1‐(2‐Naphthyl)Butane‐1,3‐Dionato(1‐)Complexes
Four new Pr(III) mononuclear complexes of formula [Pr(ntfa)3(MeOH)2] (1), [Pr(ntfa)3(bipy)2] (2), [Pr(ntfa)3(4,4′-Mt2bipy)] (3) and [Pr(ntfa)3(5,5′-Me2bipy)] (4), where ntfa = 4,4,4-trifuoro-1-(naphthalen-2-yl)butane-1,3 ...
