Short-term oleoyl-estrone treatment affects capacity to manage lipids in rat adipose tissue 

    Salas Mani, Anna; Noé Mata, Verónica; Ciudad i Gómez, Carlos Julián; Romero Romero, María del Mar; Remesar Betlloch, Xavier; Esteve Ràfols, Montserrat (2009-03-20)

    Background: Short-term OE (oleoyl-estrone) treatment causes significant decreases in rat weight mainly due to adipose tissue loss. The aim of this work was to determine if OE treatment affects the expression of genes that ...

    Treatment of pregnant rats with oleoyl-estrone slows down pup fat deposition after weaning 

    García Peláez, Beatriz; Vilà Pont, Ruth; Remesar Betlloch, Xavier (2009-03-25)

    BACKGROUND: In rats, oral oleoyl-estrone (OE) decreases food intake and body lipid content. The aim of this study was to determine whether OE treatment affects the energy metabolism of pregnant rats and eventually, of their ...

    Semiquantitative RT-PCR measurement of gene expression in rat tissues including a correction for varying cell size and number 

    Romero Romero, María del Mar; Grasa Martínez, Maria del Mar; Esteve Ràfols, Montserrat; Fernández López, José Antonio; Alemany, Marià, 1946- (2009-03-30)

    Background: Current methodology of gene expression analysis limits the possibilities of comparison between cells/tissues of organs in which cell size and/or number changes as a consequence of the study (e.g. starvation). ...

    In rats, oral oleoyl-DHEA is rapidly hydrolysed and converted to DHEA-sulphate 

    Serrano Muñoz, Marta; Grasa Martínez, Maria del Mar; Fernández López, José Antonio; Alemany, Marià, 1946- (2009-03-30)

    Background: Dehydroepiandrosterone (DHEA) released by adrenal glands may be converted to androgens and estrogens mainly in the gonadal, adipose, mammary, hepatic and nervous tissue. DHEA is also a key neurosteroid and has ...

    Different effects of hyperlipidic diets in human lactation and adulthood: growth versus the development of obesity 

    Alemany, Marià, 1946- (2011-09-14)

    After birth, the body shifts from glucose as primary energy substrate to milk-derived fats, with sugars from lactose taking a secondary place. At weaning, glucose recovers its primogeniture and dietary fat role decreases. ...

    Utilization of dietary glucose in the metabolic syndrome 

    Alemany, Marià, 1946- (2011-11-30)

    This review is focused on the fate of dietary glucose under conditions of chronically high energy (largely fat) intake, evolving into the metabolic syndrome. We are adapted to carbohydrate-rich diets similar to those of ...

    Effect of cocoa powder in the prevention of cardiovascular disease: biological, consumption and inflammatory biomarkers. A metabolomic approach 

    Urpí Sardà, Mireia; Llorach, Rafael; Monagas, Maria; Khan, Nasiruddin; Rotchés Ribalta, Maria; Roura Carvajal, Elena; Lamuela Raventós, Rosa Ma.; Estruch Riba, Ramon; Andrés Lacueva, Ma. Cristina (2012-01-09)

    Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32392

    Activities of amino acid metabolizing enzymes in the stomach and small intestitine of developing rats 

    Remesar Betlloch, Xavier; Arola i Ferrer, Lluís; Palou Oliver, Andreu; Alemany, Marià, 1946- (2012-02-17)

    The activities of aspartate and alanine transaminase, serine dehydratase, arginase, glutamate dehydrogenase, adenylate deaminase and glutamine synthetase were determined in the stomach and small intestine of developing ...

    Effects of lactation upon circulating plasma metabolites in cafeteria-fed rats 

    Salvadó, J.; Segués Piqué, Teresa; Alemany, Marià, 1946-; Arola i Ferrer, Lluís (2012-02-17)

    1. The effects of "cafeteria feeding" on primiparous Wistar rats during lactation have been studied by measuring circulating levels of glucose, amino acids, lactate, urea and ammonia as well as glycogen levels in liver and ...

    Intestinal and hepatic nitrogen balance in the rat after the administration of an oral protein load 

    Fernández López, José Antonio; Casado, Javier (Casado Merediz); Rafecas Jorba, Immaculada; Esteve Ràfols, Montserrat; Argilés Huguet, Josep Ma.; Remesar Betlloch, Xavier; Alemany, Marià, 1946- (2012-02-17)

    The fate of a small oral dose of protein given to overnight-starved rats was studied. After 3 h, 62 per cent of the protein amino acids had been absorbed. Most of the absorbed N went into the bloodstream through the portal ...

    Comparative effects of oleoyl-estrone and a specific b3-adrenergic agonist (CL316, 243) on the expression of genes involved in energy metabolism of rat white adipose tissue 

    Ferrer Lorente, Raquel; Cabot Majem, Cristina; Fernández López, José Antonio; Alemany, Marià, 1946- (2012-02-17)

    Background: The combination of oleoyl-estrone (OE) and a selective b3-adrenergic agonist (B3A; CL316,243) treatment in rats results in a profound and rapid wasting of body reserves (lipid). Methods: In the present study ...

    Rat splanchnic net oxygen consumption. Energetic implications 

    Casado, Javier (Casado Merediz); Fernández López, José Antonio; Esteve Ràfols, Montserrat; Rafecas Jorba, Immaculada; Argilés Huguet, Josep Ma.; Alemany, Marià, 1946- (2012-02-24)

    1. The blood flow, PO2, pH and PCO2 have been estimated in portal and suprahepatic veins as well as in hepatic artery of fed and overnight starved rats given an oral glucose load. From these data the net intestinal, hepatic ...

    Obesitat i control del pes corporal 

    Rafecas Jorba, Immaculada; Fernández López, José Antonio; Remesar Betlloch, Xavier; Alemany, Marià, 1946- (2012-02-24)

    L'obesitat es una malaltia mal coneguda queafecta un nombre creixent de persones arreu del mon. L'increment de la incidencia de l'obesitat en alguns paisos s'ha atribu 'it a un increment del consurn de determinats aliments ...

    Measurement of total estrone content in foods. Application to dairy products. 

    García Peláez, Beatriz; Ferrer Lorente, Raquel; Gómez-Ollés, S.; Fernández López, José Antonio; Remesar Betlloch, Xavier; Alemany, Marià, 1946- (2012-02-24)

    Estrone is a powerful growth-inducing hormone that is present in milk, mainly in the form of fatty acid esters, at concentrations that promote growth in experimental animals. We present here a method useful for the measurement ...

    Corticosterone inhibits the lipid-mobilizing effects of oleoyl-estrone in adrenalectomized rats 

    Grasa Martínez, Maria del Mar; Serrano, M.; Fernández López, José Antonio; Alemany, Marià, 1946- (2012-02-24)

    Oleoyl-estrone (OE) is an adipose-derived signal that decreases energy intake and body lipid, maintaining energy expenditure and glycemic homeostasis. Glucocorticoids protect body lipid and the metabolic status quo. We ...

    The defense of adipose tissue against excess substrate-induced hyperthrophia: Immune system cell infiltration and arrested metabolic activity 

    Alemany, Marià, 1946- (2012-02-24)

    Obesity, the excessive accumulation of body fat, is a main defining feature of the metabolic syndrome, and overweight is often an early indication of the future severity and development of associated pathologies. There is ...

    Hindleg muscle energy and substrate balances in cold-exposed rats 

    Adán Liébana, Cristina; Ardévol Grau, Anna; Closa, Daniel, 1961-; Remesar Betlloch, Xavier; Alemany, Marià, 1946-; Fernández López, José Antonio (2012-02-24)

    Rats chronically cannulated in the carotid artery and the muscular branch of the femoral vein were subjected to a cold (4 °C) environment for up to 2 h. The changes in blood flow (measured with 46Sc microspheres) and ...

    3-Hydroxybutyrate coinfused with noradrenaline decreases resulting plasma levels of noradrenaline in Wistar rats 

    Cañas, Xavier; Sanchis, D.; Gómez, G.; Casanovas, J.M.; Artigas Pérez, Francesc; Fernández López, José Antonio; Remesar Betlloch, Xavier; Alemany, Marià, 1946- (2012-02-24)

    Pentobarbital-anaesthetized male Wistar rats were infused with 6microgkg-1min-1 of noradrenaline. The infusion was supplemented with 8.5 mgkg-1min-1 of D-3-hydroxybutyrate (3-OHB) for 15 min in order to determine its effect ...

    Whole-rat protein content estimation: applicability of the Nx6.25 factor 

    Rafecas Jorba, Immaculada; Esteve Ràfols, Montserrat; Fernández López, José Antonio; Remesar Betlloch, Xavier; Alemany, Marià, 1946- (2012-02-24)

    The amino acid composition of the protein from three strains of rat (Wistar, Zucker lean and Zucker obese), subjected to reference and high-fat diets has been used to determine the mean empirical formula, molecular weight ...

    Insulin degradation by adipose tissue is increased in human obesity 

    Rafecas Jorba, Immaculada; Fernández López, José Antonio; Salinas, Isabel; Formiguera Sala, X.; Remesar Betlloch, Xavier; Foz Sala, M. (Màrius); Alemany, Marià, 1946- (2012-03-05)

    White adipose tissue samples from obese and lean patients were used for the estimation ofinsulin protease and insulin:glutathione transhydrogenase using 1251-labeled insulin. There was no activity detected in the absence ...